Search Documents

By X. Shi, K. S. Kaspnak

"The generation of free radicals from reactions of nickel (Il)-thiol complexes with molecular oxygen and model lipid hydroperoxides was investigated by electron spin resonance (ESR) utilizing 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) as a spin trap. Incubation of nickel (II) [Ni(II)) with cysteine in an aerobic environment generated hydroxyl (·OH) radical, which then reacted with cysteine to generate a carbon-centered alkyl ( · R) radical. Radical generation was inhibited under a nitrogen atmosphere. Model lipid hydroperoxides, cumene hydroperoxide, and I-butyl hydroperoxide enhanced the yield of these radicals and also generated an alkoxyl (·OR) radical. Radical yield decreased by approximately half under a nitrogen atmosphere. Although histidine did not cause radical formation in the reaction between Ni(II) and cumene hydroperoxide under aerobic conditions, the addition of histidine to a mixture containing Ni(ll), cysteine, and cumene hydroperoxide under the same experimental conditions increased the yield of · R radical but lowered the yield of ·OR and ·OH radical adducts. It thus appears that histidine caused the ·OH attack to be more site-specific. Similar results were obtained utilizing 1-butyl hydroperoxide. Penicillamine or N-acetylcysteine yielded similar results except that under aerobic conditions, reaction between Ni(ll) and N-acetylcysteine without hydroperoxide did not generate a significant concentration of free radicals. Under the same experimental conditions, cystine did not generate any detectable free radicals, suggesting an important role of the -SH group in Ni(II)-mediated free radical generation. The results indicate that free radical generation from the reaction of Ni(Il)-thiol complexes and molecular oxygen, and/or lipid hydroperoxides, may play an important role in the mechanism(s) of Ni(II) toxicity and carcinogenesis. INTRODUCTIONWhile nickel is a well-recognized carcinogen [l, 2]. the underlying biochemical mechanisms remain unclear (3, 4). Recent studies suggest that these mechanisms may involve oxidative DNA damage through free radicals, especially the hydroxyl (•OH) radical [5-13]. The mechanisms of nickel carcinogenicity and toxicity may also involve lipid peroxidation [14-21]. Unlike ferrous ion [Fe(II)], the Ni(II) cation itself does not directly react with 02, H2O2, or lipid hydroperoxides to generate free radicals [12, 21]. However, it has been reported that Ni(II) complexes with certain synthetic oligopeptides, e.g., tetraglycine or glycylglycylhistidine, make Ni(II) reactive with 02. This reaction results in transitory formation of Ni(III) and degradation of the organic ligand via free radical reactions [22]. Such Ni(II)-peptide complexes are also capable of reacting with H2O2 to produce oxygen free radicals [11, 12]. Although the cellular environ¬ment may not contain these particular peptide ligands that are known to render Ni(II) redox active in vitro, it does contain a variety of oligopeptides that are capable of forming Ni(II) complexes at physiological pH, and thus may facilitate Ni(II) redox activity in vivo. These oligopeptides include glutathione (y-L glutamylycysteinylglycine), carnosine (homocarnosine (y aminobutyryl-L-histidine), and anserine ( B-alany1-3-methyl-L-histidine)."

Nov 1, 1995

By B. Numerov

A numerical proceeding of corrections with respect to topography is worked out for places near the station and a graphical one for the remote parts of the terrain. The description is clear and very detailed. The numerical proceeding is very similar to that of the Eötvös and Schweydar methods which are in use already. In both methods the levelling is accomplished in certain circles and fixed azimuths around the station. While, in using the Eötvös method, the height differences are directly inserted into the final formulas with regard to the foot of the instrument and in case of accurate formulas derived by Schweydar the height differences are calculated with respect to the center of gravity of the attachment, Numerov introduces functions A and B, the heights, of the terrain and of the center of gravity, which are to be inserted into the formulas.

Jan 1, 1929

By Larry A. Haas

The Bureau of Mines is investigating the use of complex gas mixtures, such as would be produced by coal gasification, for reducing iron oxide pellets. A semiempirical model was developed to predict a priori the reduction rate of an iron oxide pellet in a laboratory tube furnace with simulated coal gases at a total pressure of 1 atm. The model uses partial pressures of H2, CO, CO2, CH4 (methane), water vapor, and a temperature-dependent term to predict the rate of reaction. The reduction rate (weight loss per unit of time) was determined with a thermo-gravimetric apparatus (TGA) in the temperature range of 800° to 1,100° C. The ranking of the reductants, in order of decreasing reducing potential, is H2, CO, and CH4 at temperatures between 800° and 1,000° C; however, CH4 became a better reductant than CO at 1,100° C. Water vapor did not decrease the reduction rate as much as did CO2, Carbon deposition was observed at temperatures below 1,000° C with gas mixtures with high CO and low H2 concentrations. With low-Btu gas at 900° C, over 90 pct of the iron oxide was reduced to iron in less than 3 h. This com-pares with a reduction time of 1.5 h with medium-Btu gas and 1 h with reformed natural gases.

Jan 1, 1985

By E. J. Kloos, R. H. Schutz, B. I. Ferber

To protective devices, the Bureau of Mines has established five schedules of minimum performance requirements for the approval of respirators. The current revisions of these schedules include 13D for self-contained breathing apparatus, 14F for gas masks, 19B and the amendments to 19B for supplied- air respirators, 21B for dust, fume, and mist respirators, and 23B for chemical cartridge respirators. Copies of these schedules may be obtained from the Bureau of Mines, Publications Distribution Section, 4800 Forbes Avenue, Pitts- burgh, Pa., 15213. Approval tests on respirators are performed only at the request of the manufacturer of the respirator and at his expense. If the device meets the approval requirements, a certificate of approval is granted on the complete respirator. This certificate states that as long as the respirator is manufactured as originally approved, or in accordance with any changes covered by an exten- sion of the original approval, the manufacturer may advertise and sell his respirator as being approved by the Bureau of Mines. Many industries and regulatory agencies require that respirators approved by the Bureau of Mines be used where respiratory protection is needed. The Bureau of Mines, how- ever, has no regulatory power over the use of the respirators that it approves. It acts as an impartial testing agency to insure the availability of suitable and safe respirators. At frequent intervals, the Bureau of Mines purchases approved respirators and replacement parts on the open market. These are examined for conformity to the approved status, and are checked to insure that the manufacturer's pro- duction facilities are maintaining a satisfactory quality control.

Oct 1, 1965

By M. L. Wang, S. R. Short, E. M. Daniloff, E. L. Petsonk, D. M. Mannino, G .. R. Wagner

"Background—It has been suggested that health related job selection is a major cause of the healthy worker effect, and may result in inaccurate estimates of health risks of exposures in the working environment. Improved understanding of self selection, including the role of airway hyperresponsiveness, should improve accuracy in estimating occupational risks.Methods—We evaluated symptoms of the respiratory tract, lung function, occupa¬tional and smoking histories, and airway responsiveness from a cross sectional sur¬vey of 478 underground bituminous coal miners and non-mining controls. Workers with abnormal spirometry were excluded from methacholine testing.Results—Methacholine responsiveness (= 15% decline in forced expiratory volume in one second) was associated in both miners and controls with reduced ventilatory lung function and an increased risk of respiratory symptoms. Miners with the longest duration of work at the coal face had a low prevalence of methacholine responsiveness, compared with miners who had never worked at the coal face (12% v 39%, P < 0.01). Throughout their mining careers, miners who responded to methacholine were consistently less likely to have worked in dusty jobs than miners who did not respond to methacholine.Conclusions—These results provide evidence that workers who are employed in dusty jobs are less likely than their unexposed coworkers to show increased non-specific airway responsiveness, pre-sumably as a result of health related job selection. Surveys of workers in which responsiveness data are unavailable may underestimate the effects of dust exposure on respiratory health."

Dec 1, 1996

By R. M. Jimeson

Pressure-drop measurements through beds of granular iron, lathe turnings, steel wool, and parallel-plate assemblies were made at linear velocity and gas-density ranges expected in the Fischer-Tropsch hot gas recycle process.4/ Equations relating pressure drop, linear velocity, gas density, and bed porosity were derived. The results indicate that the exothermic heat of reaction can be removed at a lower cost by using catalyst beds with high porosity. INTRODUCTION The Fischer-Tropsch hot-gas-recycle process requires a catalyst offering low resistance to gas flow as one condition to economic feasibility. Conventional granular or spherical catalysts used during early development of the process in Germany did not meet this requirement. Large pressure drops across these beds made the cost of recirculating the gas excessive. The Federal Bureau of Mines is investigating the process by using novel and unusual catalysts that offer little resistance to gas flow. Pressure-drop measurements across these types of catalyst beds are discussed in this report.

Jan 1, 1959

By T. E. Gray

This report describes preparation characteristics of the significant coalbeds in Marion County, W. Va., as determined by the Bureau of Mines. It is one in a series telling what coals are suitable for producing metallurgical coke, either as mined or after beneficiation. Over 9.4 million tons of coal was produced in Marion County, W. Va., in 1958, of which almost 6 million tons was cleaned mechanically in nine cleaning plants. All of the coal mechanically cleaned came from the Pittsburgh bed. The Bureau of Mines estimated that 1,578 million tons of recoverable coal remained in the county in beds 28 inches or more thick as of January 1, 1955.

Jan 1, 1960

By Roy Bartholomae

Noise generated by continuous mining machines in underground coal production is an important health hazard. Bureau of Mines Contract J0387229 covers investigation of this noise through laboratory tests of simulated cutting operations and through in-mine noise measurements. The results of these investigations indicate that coal cutting noise and conveyor noise are dominant sources of mining machine operational noise. Typical noise levels for both cutting and conveying operations are approximately 97 dBA (decibels A-weighted). For full operation of all machine systems, the overall sound pressure level is approximately 101 dBA. In-mine and laboratory test results show excellent agreement in both A-weighted overall levels as well as in A-weighted one-third-octave band spectra.

Jan 1, 1983

By M. M. Hassan

This report describes the analysis tools developed at West Virginia University which can be implemented to optimally design coal mine electrical systems. The basic analytical tools for all power systems are the load-flow and short-circuit analysis. Well known programs have been developed for analysis of ac transmission and distribution systems, but they are not applicable to a system which has combined ac/dc distribution, such as a coal mine power system. Furthermore, the topology of a coal mine electrcal system changes continuously due to the movement of the locomotives on the track. In the first section of this report, algorithms for carrying out load flow and short-circuit analysis of a coal mine electrical system are described. Results from the study of a typical coal mine system are presented. In the second section a method is described to optimally size power cables for cyclic loads. The method is based on the development of a thermal-electric model for a low-voltage power cable. Results from experimental verification of the model are also presented. These techniques are useful in the safe, efficient, reliable and economical design of the coal mine electrical power systems.

Jan 1, 1979

By Milton H. Fies

The dedication of thin building, establishing a station of the U.S. Bureau of vines at the University of Alabama, bristles with significance and challenges the wisdom and courage of the people of this State. Here is united, in common aim, the Engineering School of our State University, recognized for its competency and usefulness, and the Federal Bureau of Mines. The Bureau is one of the most effective arms of our National Government. It outranks in accomplishment, measured by practical scientific contribution, any like governmental organization in all the other nations. It possesses none of the characteristics of many other bureaus of government which have created popular bias. Here is one Bureau devoid of political suggestion or aim with a personnel zealously devoted to labor in scientific re¬search - an organization marked by practical accomplishment, alleviating many of life&apos;s burdens, raking easier life&apos;s pathway, and unerringly pointing to life&apos;s possibilities.

Jan 1, 1936

By Charles D. Litton

This Bureau of Mines report presents a discussion of the essential components of pneumatic monitoring systems and their associated functions. Design criteria are presented which can be used for the design and fabrication of pneumatic monitoring systems having total system response times on the order of 15 to 30 min. To illustrate the utility of these design criteria, two detailed design examples are presented,

Jan 1, 1983

By T. E. Gray

This report describes the preparation characteristics of the more significant coals in Dickenson County, Va. It is one in a series planned to determine which coals are suitable for the production of metallurgical coke either as mined or after beneficiation. Nearly 4 million tons of coal was produced in Dickenson County in 1955, of which approximately 2.7 million tons was cleaned mechanically in 5 cleaning plants. The Federal Geological Survey has estimated that nearly 1,300 million tons of measured and indicated coal reserves remained in the county as of January 1, 1951.

Jan 1, 1958

By M. L. Skow

Large tonnages of the manganese ores found in Aroostook County, Maine, are refractory to conventional mineral-dressing techniques and to the common chemical- extraction procedures. The Maple Mountain-Hovey Mountain ores are typical of this type. Because the most promising method of recovering the manganese from these ores has been a chloridizing roast in which the ground ore is in contact with gaseous hydrogen chloride, preliminary batch tests were made with a fluidized bed. On the basis of these tests, it was concluded that fluidization, with careful control of operating conditions, could be employed for this cloridization and warrants further study. Selective volatilization of the iron at 600° C. was unsuccessful. An operating temperature of approximately 950° C. was necessary for a practicable rate of volatilization of manganese chloride. Hydrogen chloride contents of 10 to 100 percent of the fluidized gas gave essentially equivalent manganese recoveries with an 80- minute retention time, For shorter periods reaction was more complete with the higher hydrogen chloride concentrations. At the 80-minute retention period the lower hydrogen chloride concentrations volatilized somewhat less iron and also improved the physical operation of the process. Fluidization gave results superior to comparable tests on chloridization in a fixed bed.

Jan 1, 1956

By C. J. Wilhelm, John M. Devine, Ludwig Schmidt

"Steel tanks often corrode rapidly in oil fields where the Gas produced with crude contains an appreciable quantity of hydrogen sulphide. In many instances working tanks have been discarded after only six months of service because of failure induced by corrosion.Aluminum has been used for some time in the fabrication of certain equipment incidental to the handling of oils containing hydrogen sulphide gas in solution, and has exhibited no carious corrosive action. These uses indicated that aluminum tanks,be equally effective in counter- acting hydrogen sulphide corrosion. Consequently, in the spring of 1920, an all-aluminum stock tank of 500 barrels capacity and a ""composite"" tank of equal capacity, having a steel bottom and bottom ring and an aluminum top and top ring, were placed in service on the State-Lassiter lease of the Gulf Production Co, in Crane County, Tex. These tanks were under observation for one year, the toot being sponsored by the Gulf Production Co., the Aluminum Co. of America, and the Parkersburg Rig and Reel Co. The results of this preliminary test sustained the belief that aluminum is highly resistance to hydrogen sulphide gas and likewise indicated the type or grade of aluminum which could be most economically used for lease tankage. However, in this preliminary test the tanks were not subjected to contact with the quantities o highly concentrated brines such as often are associated and produced with crude oil. Therefore, it was suggested by representatives of the aluminum Co. that additional tests be made to include production conditions in large quantities of brine would be handled, for pact experience had shown that aluminum often is susceptible to the corrosive action of brines."

Apr 1, 1931

By Donald F. Reed

The bauxite deposits of Tippah and Benton Counties in northeastern Mississippi were developed by drilling as a part of the investigation by the Bureau of Mines of the domestic sources of supply of aluminum. The primary purpose of investigations of this nature was to provide essential information to the war agencies of the United States Government and to assist owners and operators of mining properties in the production of minerals vital to the prosecution of the war. These reports are based upon the field work of the Bureau of Mines and upon data made available to the Department from other

Jan 1, 1948

By E. G. Baglin

The Bureau of Mines devised a procedure for selectively extracting platinum-group metals (PGM) and gold from Stillwater Complex flotation concentrate. The Stillwater Complex is the only major U.S. PGM resource. Development of a suitable extraction technique will contribute to its exploitation. The concentrate was roasted at 1,050° C to convert host base-metal sulfides to oxides and the PGM from sulfide minerals to their elemental states. The roasted concentrate was preleached with dilute sulfuric acid to remove easily soluble gangue minerals. After pre-leaching, the concentrate was slurried with 6M HCI and leached at ambient temperature and pressure with a strong-oxidizing agent. Hydrogen peroxide, chlorine, sodium hypochlorite, nitric acid, and a persulfate salt were the oxidants investigated. The two-stage leaching scheme ex-tracted up to 97 pct of the platinum, 92 pct of the palladium, and 99 pct of the gold from the roasted concentrate. The base metals were not solubilized and reported to the residue. No attempt was made to devise a procedure to recover the copper and nickel because they comprise less than 5 pct of the value of the concentrate. Viable techniques for recovering the precious metals from the pregnant solution were sulfide precipitation, cementation with nickel, or adsorption on activated carbon.

Jan 1, 1985

By H. L. Riley, B. W. Gandrud

"INTRODUCTION The Bureau of Mines, United States Department of the Interior, with the cooperation of the University of Alabama and coal producers, has made a series of washability studies to obtain technically and commercially important data regarding the productive coal beds of the State. Based on the system followed in these studies, this report consists principally of screen-sizing and float-and-sink data on the Clark and Gholson beds at Boothton, Ala. A previous washability study 4/ has been made on the Clark bed at Marvel, Ala.SAMPLING AT MINESThe coal from the Gholson and the Clark beds was sampled at the tipple which receives the output,the Boothten No. 3 and No. 4 mines. These two mines are on the Gholson and Clark beds, respectively, but the coal. from both mines is mixed on the tipple and washed in the same washery. The samples taken were minus 4-inch raw coal. The plus 4-inch raw coal is hand¬picked and not washed. AS the 4-inch screen had a capacity in excess of the output of the mines, it was stopped at the end of each mine-car trip. By Observing from which mine incline each trip was hoisted, a separate sample from each bed was cut from the discharge stream of an endless belt which conveys the through 4-inch raw coal to the bin ahead of the washer. The output from each bed was sampled uniformly over the period of a working shift. The two washability samples weighed approximately 3,000 pounds each."

Dec 1, 1947

By James M. Nishi, Lloyd Carpenter

Sixteen elements were determined spectrochemically in the general range of 3 to 1,000 ppm in high - purity columbium . Samples were converted thermally to Cb2 O , mixed with graphite and Ge02 , and excited for 15 seconds using a 15 - ampere dc arc . For the molybdenum determination , the oxidized samples were mixed with NaCl and Geo₂ and excited for 30 seconds . Spectra were recorded on photographic plates , and spectral line transmittance values were measured photometrically . Relative - intensity ratios of selected analytical and internal standard spectral lines were plotted against concentrations of standards to form curves from which concentrations of impurities were read . Average precision of the method was 11.2 percent relative standard deviation .

Jan 1, 1964

By Martin J. Gavin

The oil- shale studies of the Bureau of Mines , conducted in cooperation with the State of Colorado and the University of Utah , have for their primary purpose the determination of retorting and refining conditions most favorable for obtaining the highest yields of most satisfactory products . Oil shales , typical of the deposits in several States , are retorted in carefully controlled retorts of differe types , the conditions being varied in successive runs as the results indicate that improvement in the yield and quality of the products most desired may be expected . Each shale presents a somewhat different problem , for it has been found that different shales treated under similar conditions yield products of different natures , and also that the same shale will yield products of different natures when retorted under different conditions . Some shales apparently can not be made to yield , under any set of conditions , products of so high an order as are yielded by other shales . This indicates that the oil -yielding materials of certain shales differ in constitution and in their manner of breaking down when undergoing destructive distillation . Other shales appear to contain oil - yielding materials that resemble each other closely as regards chemical constitution , yet they require some. what different conditions of treatment , if products of similar nature are to be produced from each . In such cases the controlling factors seem to be the richness of the shale that is , its content of oil -yielding material and the physical and chemical nature of its mineral parts .

Mar 1, 1922

By Stephen A. Hare, O&apos

Powder metallurgy processing of commercial Raney nickel powders was examined. The typical angular particle shape, in conjuction with aluminum present in a eutectic phase, facilitated interlocking leading to excellent green strength after compaction. Density and porosity as influenced by the compacting pressure were studied over the range of 37.5 to 207 meganewton per square meter (MN/m2). Sintering in an inert atmosphere from 575° to 850° C caused a volume increase which is attributed to a solid state reaction between Al and Ni2Al3 phases. The reaction is 3Al + Ni2Al3 ? 2NiA13. A thermal pretreatment of 70 hours at 700° C was required to prevent this reaction from occurring during sintering. Density and porosity as a function of compacting pressure and sintering temperature were determined after a thermal pretreatment of the powder.

Jan 1, 1976