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By D. D. Misra

Though computer simulation of coal beneficiation has been in use for nearly two decades the models used in the programs for the simulation of the crushing processes concentrate mainly on the size distribution. This paper suggests the use of an empirical equation approximating to the cumulative probability or error function for the simulation of the liberation process in coal crushing. The algorithm outlined here can be incorporated in a computer program already having a size distribution model.

Jan 1, 1989

Metana Minerals commenced life in 1970 and graduated to a mining company in 1981 with the opening of a small alluvial tin-tantalite mine at Wodgina (W.A.) The present board of directors assumed control of the company in 1978 and established the exploration and development philosophies that have guided the company's expansion to its present status as an emerging diversified miner. An ability and willingness to raise equity capital when required has been a feature of the company. Company activities include exploration for gold, diamonds, heavy mineral sands, polymetallic (base and precious metals) deposits, strategic minerals, rare earths, oil and gas in a geographical distribution covering the entire Australian mainland Metana owns and/or operates four gold mines (Reedy, Mt Magnet, Youanmi and Howley) and at the time of writing is developing a fifth gold mine - its first underground mine - at Rothsay. In contrast to many similar or larger sized companies, Metana undertakes most activities itself rather than through the use of consultants or contractors. In-house services include: analytical and metallurgical laboratories, plant engineering design and construction, drilling and mining (earthmoving) Metana Minerals has established an enviable reputation for technical excellence and this expertise has placed the company in a sound position to continue its growth pattern into the future. This growth will be achieved through a combination of low cost and successful exploration and acquisition of suitable mines either directly or through corporate activity.

Jan 1, 1989

By Barry N. Doyle, Tarcisio M. Carvalho, Alan K. Haines, Marcos P. de Melo, Edward J. da Silva

A metallurgical complex to recover gold from highly refractory arsenical ore was recently commissioned by Sao Bento Mineraco. The plant, with a nominal capacity of 20 000 tonnes per month, is situated in the Minas Gerais province of Brazil. The process consists of run-of-mine milling, flotation, pressure oxidation of the concentrate, carbon-in-leach, elution and electrowinning, and effluent disposal. The paper provides an account of the investigations that resulted in the decision to install the pressure oxidation circuit, process and engineering design and plant start up. A comparison is made between the results achieved during the first two years of production and the design parameters.

Jan 1, 1989

By J. D. Morgan

The US economy continued to grow steadily in 1988, reaching an annual rate of $5 trillion in the last quarter (US trillion = 1012). The value of domestically processed mineral-based materi¬als rose 20% to $300 billion (US billion 109). The value of metals produced from US ores rose 40% to more than $10 billion, industrial minerals rose 6%' to $20 billion, and recycled scrap more than doubled to $10 billion. Increasing economic activity stimulated metal prices. Yearly lows and highs were 95 cents and $1.68 for copper, 52 cents, and $1.30 for aluminum, 34 cents and 42 cents for lead, and 43 cents and 75 cents for zinc. A number of mining and metal companies experienced significantly increased profitability. Consumer demand strongly affects mining because the US economy is relatively saturated with long-lived products. Consumer, mortgage, and Federal debt continued to rise. About 246 million US citizens already possess 170 million licensed motor vehicles and 100 million dwelling units. New car production remained at the 1987 level of 7.1 million units. Truck and bus production, however, rose 7% to 4.1 million units. New housing starts fell 7% to 1.5 million units. Imports supplied a significant proportion of total US consumption of several important mineral materials. By year-end, imports of crude and refined petroleum exceeded domestic crude oil production. Such imports cost $42 billion. Imports of nonfuel mineral-based materials were valued at $44 billion and exports at $35 billion. The US and Canada-the world's two largest trading partners-consummated a historic free trade agreement. In February, President Reagan transferred responsibility for stockpiling strategic and critical materials to the Secretary of Defense. And, in July, the GSA group that bought, stored, rotated, and sold stockpiled materials was transferred to the Defense Department's Defense Logistics Agency. Concern about apartheid in South Africa continued, resulting in increasing attention to chromium, manganese, platinum-group metals, cobalt, vanadium, and gold. The Defense Production Act, authorizing priorities and allocations, supply expansions, voluntary agreements, and the National Defense Executive Reserve, was amended to include provisions for averting harm to national security from foreign takeovers. The DPAct, in effect through September 1989, is now up for further extension. Under the Act, the US Bureau of Mines maintains the Emergency Minerals Administration. During the year, consultations were held with Canada to strengthen the North American Defense Industrial Base. Coal production, 60% from open pits, rose 5% to 870 Mt (960 million st). Nearly four-fifths was burned to generate 57% of US electricity. Exports included 56 Mt (62 million st) of metallur- gical coal and 29 Mt (32 million st) of steam coal, with a total value of $4 billion. Domestic petroleum produc¬tion fell 2% to 574 hm3 (3.6 billion bbl). Uranium mining, including recovery from phosphates, was unchanged at 5.9 kt (6500 st). Nonfuel minerals Major metals Raw steel production-a major con¬sumer of many minerals-rose 14% to 92 Mt (102 million st). Domestic iron ore production rose 25% to 59 Mt (65 million st), about 96% pelletized. Net imports rose 37% to 16 Mt (18 million st). Raw steelmaking capacity of 102 Mt (112 million st) was unchanged. Voluntary Restraint Agreements with 21 steel exporting nations limited im¬port penetration to about 20% of the domestic market. Domestic producers of bulk ferroal¬loys of chromium, manganese, and sili¬con operated at about 75% of capacity. The US mined no manganese or chro-

Jan 1, 1989

By Hsing Kuang Lin

Ferric chloride leaching w.as applied to a complex sulfide ore from Tok, Alaska to dissolve zinc, lead, silver and copper. Gold in the leaching residue, as well as in the ore, is found to be refractory to the conventional cyanidation process. Roasting, pressure oxidation and elemental sulfur removal followed by cyanidation were tested to improve gold dissolution. Also tested were thiourea leaching and high-pressure cyanidation. The readsorption of dissolved gold by carbonaceous matter in the chloride leaching residue was analyzed. Based on the experimental results, factors causing difficulty of gold dissolution from the leaching residue are discussed.

Jan 1, 1989

By C. Van der Veen

The use of the quasi static (Dutch) Cone Penetration Test (CPT) is described as a tool to predetermine the ultimate bearing capacity of the pile point. An analysis is given why a purely theoritical approach does not meet with success. A practical method is explained of extrapolating the cone resistance to predict the pile point resistance. The method has been calibrated against the result of 32 selected high standard loading tests on pile points in the Netherlands.

Jan 1, 1989

By Robert F. Chaiken

More than 500 fires are now burning in abandoned coal waste banks and coal deposits in the United States. Once established, such fires can burn for decades, and extinguishing them by conventional methods such as surface sealing to exclude air, excavation to remove fuel, or flushing to cool the fire zone is usually difficult and always expensive. Burnout Control, a technique developed by the Bureau of Mines for the control of abandoned coal fires, involves the accelerated combustion of coal in place with total management of the heat and fumes produced. A burning waste bank or mine is placed under negative pressure relative to the atmosphere, and heat and combustion products are drawn from the combustion zone through an exhaust ventilation system. Heat produced appears as sensible heat in the exhaust, at temperatures as high as 1,000° C (1,832° F), and could be recovered for the production of steam, hot water, process heat, or electricity. The Bureau's first field demonstration of Burnout Control was at Calamity Hollow in Allegheny County, PA (near Pittsburgh). Calamity Hollow was the site of an underground mine in the. 1900's and was surface mined in the 1940's. In the winter of 1961~62, a fire of undetermined origin was discovered in the exposed coal. In 1963, the Bureau constructed a trench barrier around the fire and a surface seal over the affected area. The fire was isolated but, not completely extinguished. In 1979, when the Bureau began work on the Calamity Hollow Mine Fire Project to demonstrate controlled burnout, the fire was still smoldering on the hot side of the trench barrier. The project, which was begun in December 1979 and ended in July 1982, consisted of the design, construction, operation, and subsequent dismantling of a Burnout Control ventilation system. This report, although considered part 2, is actually the last of a five-part series that describes the Calamity Hollow Mine Fire Project. It was written last because it involved the analysis of a substantial body of data describing in detail the results of a continuous 4-month burnout operation. The first report, part 1, describes the design and construction of the field installation. Part 3 describes the instrumentation used to control and monitor the progress of the burnout operation. Parts 4 and 5 deal with the closeout phase of the field demonstration. Part 4 describes the procedure used to quench the fire, and part 5 describes the final excavation and backfilling of the heated zones. The reports in this series document the Calamity Hollow controlled burnout demonstration, which showed that (1) controlled in situ combustion is a feasible method for controlling underground fires in abandoned mines, (2) the resultant thermal exhaust output is suffIcient for energy utilization, and (3) water injection-fume exhaustion is a potentially effective method for cooling large underground fire zones. Further investigations of both Burnout Control and the water injection-fume exhaustion quenching procedure are planned.

Jan 1, 1989

By Jeffrey M. Listak

This report describes a study, conducted jointly by BethEnergy Mines Inc. and the Bureau of Mines, to assess the effects of longwall front abutment loading on various supplemental support materials utilized in a predriven recovery room. The purpose of the predriven recovery room is to reduce longwall equipment transfer time by eliminating the premove preparation associated with conventional recovery methods. In addition, the room provides a large area in which face salvage equipment can maneuver. Results of four recovery-room study areas show the progression and influence of the front abutment on the longwall panel and supports and their subsequent behavior. The best performance (i. e. the support that most facilitated recovery) of support material was achieved through the use of a concrete mixture which had a sand content of 35 percent by volume. The longwall transfer time was reduced by 30 percent which translates to a production advantage of 37,000 raw tons of coal per panel.

Jan 1, 1989

By W. J. Grose

The Embankment Place office development over the platforms of Charing Cross Railway Station in London has presented many interesting and unusual problems to the engineers involved with the project. The main structure is supported on widely-spaced columns which penetrate the station platforms and underlying vaults, calling for high capacity foundations built in severely restricted spaces. Hand-dug underreamed piles were chosen. Whilst a conventional design approach was taken to size the piles, a detailed appraisal of ground movements was made to explore the effects of the new building loads on the existing foundations, not only beyond the site perimeter but also those amongst the new foundations. Before construction of the pile proper could take place, it was necessary to sink a caisson through the upper unstable and water-bearing soils. This being identified as a high-risk item, a full-scale trial was carried out prior to embarking on the main works. The twenty-one hand-dug piles were 2.5m diameter, over 30m deep and belled out to between 4.5m and 6.6m.

Jan 1, 1989

By C. J. A. Davie

"SUMMARY A practical application of nitric acid oxidation of sulphides, based on the principles of the Arseno process, has been developed for the Cinola ore. Development of the process has been based on testwork conducted by Bacon Donaldson of Vancouver and Hazen Research of Denver, and on conceptual engineering performed by Minproc Engineers of Denver.A comprehensive Stage II report for the project has been submitted to the B.C. permitting agencies, containing provisions for a zero discharge tailings impoundment system and prevention of acid mine drainage. Approval in principle is expected in early 1989.A feasibility study recently completed by Minproc Engineers and Davy McKee Corporation demonstrates that this project can be brought to production for a capital expenditure of C$120 million for a mill throughput of 6,000 tonnes/day and operated at a total direct operating cost of less than $20/tonne.INTRODUCTION The Cinola orebody was discovered in 1970. It is situated approximately in the centre of Graham Island, the largest of the Queen Charlotte Islands. It represents the mid to upper levels of a hydrothermal precious metals system, characterized by intense brecciation and silicification. Gold is associated with finely disseminated sulphides in a breccia matrix and in free form in numerous quartz veins.Ownership of the property has changed hands a number of times, and previous attempts to bring the property to production have failed. Two critical factors have frequently been blamed for difficulty in creating a successful project: namely, process and environment factors, hence the title of this paper.City Resources (Canada) Limited (""City"") acquired the property in 1986, and commenced an aggressive campaign to verify ore reserves, to carry out metallurgical research and to address environmental issues.PROJECT OVERVIEW When the Cinola orebody was discovered, the significance of hydrothermal mineraliza¬tion associated with crustal plate boundaries was not recognized, and for several years, the orebody was considered an uneconomic curiosity. If the type and location of orebody sought by many companies engaged in gold exploration were to be specified, it would probably be a description of the Cinola orebody - it is a large (greater than 1.5 million ounce), low grade (2.45 gm/tonne), refractory ore reserve associated with the Pacific rim crustal plate boundary. The industry appears to have recognized in the past few years that its future lies in the exploitation of such orebodies, and is prepared to come to grips with the technical problems associated with such ores. In this sense, the Cinola orebody might be considered to have come of age."

Jan 1, 1989

By Gilles Rousset

This paper presents laboratory experiments conducted on hollow cylinders samples. The advantage of such a geometry is to approach in situ conditions around cylindrical openings (lined galleries, boreholes, ...). Many authors have been interested in this kind of problem, especially for borehole stability applications (for references see Guenot 1987). However, as long as we know, time-dependent behavior has not been well studied. For this purpose, we have set up two different types of tests on a deep clay : - Quick unloading test, to assess the influence of unloading rate on mechanical response and the failure modes. - Creep and relaxation test, to compute the time dependent overall deformation of the hole wall as well as to plot long term convergence-confinement pressure curve. The experimental results are then compared with those given by a theoretical model developed in our laboratory, well fitted with the tested material.

Jan 1, 1989

By E. Fregeau-Wu

The mineralogy and grain size distribution of phases in a steelmaking slag and experimental products from the heating of the slag under various conditions were determined to explore the possibility of recycling of the iron and manganese to the blast furnace. The steelmaking slags consisted of three major phases: dicalcium silicate, dicalcium ferrite, and Mg-Mn-wustite. Most of the phosphorus was contained in the dicalcium silicate and to lesser extent in the dicalcium ferrite. Due to the fine grain size of the dicalcium silicate, grinding and magnetic separation required pretreatment to increase the grain size and hence the liberation. Experiments on a steelmaking slag were conducted by heating the slag to 1633-1748°K( and slow-cooling in an inert atmosphere at various rates with or without the addition of fluorspar (CaF2) as a flux. Grain size distribution analyses of the starting material and the slow-cooled products were performed using the SEM-IPP area scan method and the QEM*SEM linear scan method. Comparable and reproducible results were obtained on the same sample using both methods. A size versus volume percent plot showed the increased grain growth most effectively. Examples of the grain size distributions obtained were used to show that a higher soaking temperature prior to slow-cooling, a slower cooling rate, and the addition of fluorspar to the slag promoted grain growth.

Jan 1, 1989

This report has been prepared in response to a request by the Bureau of Land Management (BLM) Fairbanks Alaska District Office that the Bureau of Mines quantitatively assess the potential supply of minerals from undiscovered deposits in the White Mountains National Recreation Area (WMNRA) and the western part of the North Steese National Conservation Area (SNCA) in Alaska. The assessment will be used to assist in future land-use decision-making. Resource Management Plans (RMPs) for the WMNRA and the SNCA were approved by the BLM in 1986. These plans imposed significant restrictions on new mineral development in the two areas. The level of public concern regarding these actions, especially on the part of the mining industry, has spurred BLM to seek additional information about the potential supply of minerals from the two areas with assistance from the Bureau of Mines. The assessment focuses on an area within the WMNRA and the SNCA which has been administratively closed to mineral entry. The study area encompassed approximately 1.24 million acres and included all of the WMNRA and the western portion of the North SNCA (fig. ES-1). Three quantitative estimates of the potential supply of minerals from the study area were developed: 1) For all lands in the study area, assuming that they are open to mineral entry-the baseline analysis; 2) For those lands which have been closed to mineral entry; and 3) For eleven prospective mineral activity areas, assuming that all are open to mineral entry.

Jan 1, 1989

By J. N. Greaves

Investigations were conducted by the U.S. Bureau of Mines to develop flowsheets for the recovery of tungsten and gold from four Alaskan scheelite-bearing ores. Basic gravity concentration and cyanide leach tests were performed on all samples. About 46 pct of the tungsten and 30 pct of the gold from one sample were recovered in a gravity concentrate containing 24 pet W03 (tungstic oxide) and 119 troy ounces per short ton (tr oz/st) Au. Froth flotation of the gravity concentrate resulted in separate tungsten and gold products with grades of 38 pct W03 and 2,720 tr oz/st Au and recoveries of 60 and 97 pet, respectively. Additional gold was recovered from the gravity and flotation tailings by cyanidation. Overall recoveries of tungsten and gold from this sample were 28 and 94 pet, respeetively. A flowsheet with mill design parameters was developed that consisted of (1) free gold and scheelite recovery by gravity methods and froth flotation and (2) fme-grained gold recovery by cyanide leaching of reground gravity and flotation tailings, followed by a carbon-in-pulp (CIP) circuit. Data were developed from the Bond mill work index, gold and tungsten flotation, conventional and high-rate thickening, cyanide leaching, and CIP adsorption tests.

Jan 1, 1989

By W. R. Gunter

"INTRODUCTIONThis article documents the current non-metallic mineral s resources of Manitoba (Fig. I), and makes comparisons with currently producing deposits in North America and elsewhere in the world. Industrial minerals may lack the glamour of gold, silver or the base metals, but they contributed approximately 20070 to the value of Manitoba's raw materials, and even out-performed our petroleum industry, except during the oil boom of the early eighties (Fig. 2). Values per tonne of industrial commodities can be as high or higher than for base metal ores. Commodity prices (Canadian), listed in the February 1988 issue of Industrial Minerals magazine, are: talc $202.00 - $306.00, sillimanite $427.00; kaolin $69.00 - $270.00; garnet $175.00 - $250.00; and mica $405.00 - $540.00. The prices are converted to Canadian dollars using the prevailing exchange rates of February I, 1988. Some commodities are not sold by weight. Building stone, for example, is sold by the cubic foot. An average rough granite block, 4 ft by 4 ft by 8 ft, is worth approximately $2000 sitting on the quarry 1100r in southeastern Manitoba (Fig. 3).Thus, not all rocks that do not contain sulphides are worthless. Some may be extracted more profitably than either the base or precious-metal bearing varieties.Industrial Mineral CommoditiesThe commodities available in Manitoba are described in two categories: (1) those already in production that have additional development or expansion potential, and (2) those not in production logical information available at this time.Current Industrial Mineral ProductionThe commodities described herein are currently in commercial production in Manitoba (Fig. 4). These mineral products also have good market expansion potential provided additional geological and market research is conducted. The use of company names in reference to sundry products and locations should not be interpreted as specific endorsement by the Government of Manitoba. The numbers following the commodity name refer to Figure 1. that have good development potential on the basis of geo-"

Jan 1, 1989

By Ken Hester, Bruce Arthur

"Introduction""Pebble milling"" is a term used to describe secondary grinding done with rock pebbles rather than steel balls or other steel or metal shapes. This paper discusses pebble milling with particular attention being paid to uranium grinding circuits.Pebble milling is typically employed:a. where the cost of steel balls becomes exorbitant, as may be the case in an isolated area.b. where the extra steel added from steel ball consumption may be detrimental to further processing.c. where the over-all economics favour the use of pebbles rather than ball.Pebble milling differs from autogenous and semi-autogenous grinding in that a sized product has been removed from some part of the primary comminution circuit, and it is this sized product which is added as grinding media to the pebble milling stage. The pebbles do not necessarily have to be produced from the ore- ""foreign"" pebbles can be used. Also, pebble milling generally refers to grinding from a fine size, below about 6 mesh (3360 micron), with relatively small media, that is, secondary grinding. In South Africa, however, primary pebble mills are sometimes used to grind crusher house product, and thus function in place of rod mills. Pebbles for this service are large and heavy as they must weigh as much as balls used in similar service.The first large applications of pebble milling were in South Africa(n. ""Tube milling"" with pebbles started in 1904. The tube mill was simply a tumbling mill with a length to diameter ratio over two. A ""typical"" early tube mill was 5.5 ft. (1.7 m) in diameter and 16 ft. (4.9 m) in length. Diameters increased steadily. King(n mentions 8-ft. (2.4 m) units in his 1949 book. By 1961, the largest units discussed by Jackson('' were 12ft. (3. 7 m) in diameter."

Jan 1, 1989

By Peter N. Calder, J. L. Workman

There are many opportunities for computers to assist in dragline mine planning. Three important areas particularly lend themselves to computer assisted study. These are overall mine design and planning, the computation and display of range diagrams and the calculation of production and production variability. The computation of range diagrams is of particular interest because of the importance of matching the dragline and site geometries. This paper examines the uses of range diagrams in dragline mining and illustrates the application of computer techniques to the computation using one such program as an example. The use of computer generated range diagrams for machine selection, pit design and in parameter analysis is discussed. Directions for further development are also provided. There is a great deal that can be done to additionally enhance the ability to provide accurate designs for the dragline operation. One area that needs special attention is the dumping of overburden around access ramps into the pit. This situation is one of the most difficult dumping sequences and affects machine selection and pit operation. It is also suggested that programs that simulate the production schedule of the drag-line would be useful. It is concluded that large overall mine planning programs are very important in dragline mining. However, smaller programs designed for a specific, task are also important tools in many cases. These are easy to learn and use, well adapted to the PC environment and provide useful information, both for design and for daily planning.

Jan 1, 1989

By Sean Gallagher

This report describes research by the Bureau of Mines on alternative materials-handling strategies for reducing the costs and incidence of back injuries in low-seam coal mines. Strategies recommended for redesigning materials-handling tasks include elimination of tasks, mechanization of tasks, and matching lifting tasks to the physical capabilities of underground miners. The report also discusses other methods that can be used by management to reduce the costs associated with back injuries.

Jan 1, 1989

By R. Hogg, S. Chander

"INTRODUCTION The behavior of particulate systems in general is determined by the properties of the solid and fluid phases and of the interfaces between them. As particle size is reduced, the inter facial effects become increasingly important until, in colloidal systems, they become completely dominant. Interfacial phenomena are especially important in coal processing for a variety of reasons. Because coal is naturally hydrophobic and its density is low, surface forces begin to dominate over gravity at relatively coarse sizes. Coal is thermodynamically unstable in the presence of air, so that surface oxidation occurs readily leading to important variations in surface properties with time and environment. These effects are further compounded by the inherent heterogeneity of the material.Surface characteristics and properties play a significant role in most aspects of coal processing. Comminution, for example, is a process of creating new surface, while agglomeration involves the reduction of surface area and is usually controlled by surface forces. Both solid-solid and solid-liquid separations are influenced by interracial phenomena, Gravity separations are usually performed in a liquid phase and are affected by the wetting characteristics of the various solids present and by the need to ensure proper dispersion of the individual particles. Froth notation, of course, separates particles on the basis of differences in surface characteristics. Chemical processes such as leaching generally involve interfacial reactions whose rates depend on surface area and may be influenced by electrochemical effects in the electrical double layer at the solid-liquid interface, or by adsorption of reactant and/or product species from solution. Solid-liquid separations and associated processes such as flocculation are strongly dependent on the nature and properties of the solid-liquid interface.In characterizing solid surfaces, it is important to consider first the surface area, since this determines the relative importance of the interfacial effects. The structure and chemical composition of the surface may depend on the distribution of different petrographic constituents and impurities such as finely disseminated mineral matter, on the extent of surface oxidation, and on adsorption from the environment. These, in turn, will generally determine the surface properties which define particle behavior. Since the relationships between structure etc. , and properties are not generally known, it is usually necessary to measure properties such as wettability and electrical charge directly."

Jan 1, 1989

By N. S. Dalal, X. N. Hu, X. Shi, V. Vallyathan

"Although silicosis has been studied extensively, the mechanism is still not fully understood. Experiments do provide evidence that the actions of unique properties of silica surface on the cell membrane are the starting point of silicotic processes. This paper summarizes literature on chemical properties of silica surface, and the effect of particle size on silica toxicity. This paper also discusses the ways in which silica dusts are thought to interact with the cell membrane, with emphasis on freshness, hydrogen bonding, and free-radical interactions.INTRODUCTIONSilicosis is a debilitating pulmonary disease that afflicts persons (miners, foundry workers, ceramic workers, heavy construction workers, etc.) who chronically inhale silica-containing dusts (Schepers, 1960; Silicosis and Silicate Disease Committee, 1988). Since silica is second only to oxygen in weight percentage of the earth's crust (about 28%) and is found in an enormous diversity of minerals, it is natural that silicosis is one of the major industrial health hazards all over the world. Although silicosis has. been studied extensively, the mechanism by which the dusts exert their toxic actions on cells and the processes by which these actions progress to fibrogenesis are still poorly understood. The biological characteristics of the dusts are largely unknown, although it is suggested that the dust size, shape, surface charge, roughness, surface chemical composition, trace metal content, and crystallinity; dose of silica in the ambient air of the workplace; duration of exposure; genetic variation in exposed subjects; personal respiratory patterns; and presence of any coexisting disease (such as tuberculosis or rheumatoid arthritis) all influence the expression of silicosis (Koskinen et al., 1983; Noweir et al., 1980; Raask and Schilling, 1980; Reiser and Last, 1979; Thorne et al., 1985; Wolff et al., 1981). The actual biochemical mechanisms through which these factors operate are still unclear. However, the experiments do provide evidence that the actions of certain unique properties of silica surface on the cell membrane are the starting point of the silicotic process (Allison et al., 1966; Allison and Harrow, 1971; Bateman et al., 1982; Marks, 1957; Parazzi et al., 1968; Reiser and Last, 1979; Summerton et al., 1977). This article summarizes literature on chemical properties of silica dusts and how silica dusts are thought to interact with the cell membrane, with emphasis on hydrogen bonding and free-radical interactions."

Jan 1, 1989