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By P. R. Miles, J. K. H. Ma, J. Y. C. Ma, L. Bowman

"The bisbenzylisoquinoline alkaloids are compounds which can be isolated from plants and which exhibit a broad range of pharmacological activities. Perhaps the best known alkaloid of this group is tetrandrine (TT), a compound isolated from the root of a traditional Chinese medicinal herb, Stephania tetrandra. It has been tested for its effects on the cardiovascular system, tumors, and the lungs. For example, tetrandrine has been shown to act as a calcium entry blocker in cardiac sarcolemmal vesicles (King et a/., 1988) and has been used in China as a treatment for angina and hypertension. Its possible effects as a tumor-inhibitory substance have also been investigated (Kupchan and Atland, 1973). In addition, there are several lines of evidence to suggest that it is a possible therapeutic agent for the treatment of silicosis. Yu et a/. (1983) have shown that TT inhibits the development of experimental silicosis in rats when it is administered orally after intratracheal instillation of quartz. Other studies have shown that the alkaloid inhibits the synthesis of collagen by fibroblasts and the formation of silicotic nodules in rats exposed to silica (Huang et al., 1981; Liu et al., 1983). In fact, tetrandrine has been used clinically in China as an antifibrotic agent and has been shown to improve both the appearance of chest radiographs and the measurements of diffusing capacity in patients with silicosis (Li et al., 1981).Since tetrandrine may have a potential use as a therapeutic agent for fibrotic lung diseases, its effects on various pulmonary cells and tissues should be studied. Alveolar type II cells are located in the alveolar regions of the lungs and are important because they are responsible for the synthesis and secretion of pulmonary surfactant (Dobbs et al., 1982; King, 1984), regeneration of the alveolar epithelium after lung injury (Kauffman et al., 1974), and metabolism of foreign compounds (Bend et al., 1985). Furthermore, in silicosis, for which TT has been suggested as a treatment, there are increased amounts of pulmonary surfactant produced (Dethloff et al., 1986a,b) as a result of increased rates of surfactant synthesis by type II cells (Dethloff et a/., 1989; Miller et al., 1988). Because type II cells play a critical role in maintaining normal lung function and because type II cells are affected in silicosis, for which 'TT has been used as a treatment, we studied the effects of tetrandrine on energy metabolism in these cells in vitro. Energy metabolism was chosen because it is a basic cellular function which is neces-sary for other cellular processes to occur. Since type II cells depend on mitochondrial metabolism for energy production (Fisher et al., 1980), we examined the effects of tetrandrine on cellular and mitochondrial ATP production and oxygen consumption. Additional experiments were performed in an effort to determine if intracellular calcium levels may be involved in the TT-induced effects. A preliminary report of those results has appeared previously (Ma et al., 1991)."

Nov 1, 1995

By H. O. Harju

In July 1968, P.T. Inco Indonesia was granted a Contract of Work to explore and develop the nickel laterite resources on the southeastern peninsula of the island of Sulawesi. Since 1970, exploration has centred on the deposits at Soroako as the site for initial project development. This paper describes the exploration methods used to evaluate these rather unique laterite deposits, the geology of which is described in the first section of this volume.

Jan 1, 1979

Various factors influence the exploration geologist or geochemist in his choice of.an analytical method for gold and other elements which may help him find the elusive gold deposit. One of the first decisions the geologist must make is the nature of sample media to collect for his survey. Needless to say there are many media available depending on the situation. These include rocks, soils, heavy mineral concentrates (from overburden drilling and panned concentrates), humus, vegetation, water, lake bottom sediments, stream sediments, etc. The choice of the sample media will depend to a large degree on the state of development of the particular project from grassroots to mine feasibility. The nature of the geological information required will affect which media and which analytical technique should be chosen for the analysis. Valid sampling from the initial sample collection, preparation and subsampling aspects may also help to determine which analytical procedure is best. Cost and turnaround time are of prime. importance to the explorationist, as it should be, however, these aspects should not be detached from receiving accurate and reliable results.

Jan 1, 1987

By Rambabu Pothina, Rajive Ganguli

The economics of a mineral-processing circuit is dependent on the numerous sensors that are critical to optimization and control systems. When a sensor goes off calibration, it results in errors that can have a severe impact on plant economics. Classical statistical approaches fail to detect when errors are “subtle,” unless they grow and become large enough to be “gross,” whereas methods based on signal processing and artificial intelligence fail in dealing with the complexity of process fluctuations. Due to the sheer volume of sensors, undetected errors are not remedied until the next calibration, which on average are a year apart across all industries [1]. This research aims to detect such subtle errors (2 percent bias) in shorter time spans of about a month — rather than wait for errors to grow — using innovative data-mining techniques and algorithms.

By Neil D. Donnell, O&apos

Bituminous sands of the Lower Cretaceous McMurray Formation in northern Alberta constitute the ore for the surface mining operation at Syncrude Canada Ltd. These sediments represent a complex succession of fluvial, estuarine and marine depositional environments. Grade prediction is realized through a combination of geological interpretation, computer modeling, and reference to past mining experience. Accurate forecasts of feed grade permit reliable predictions of volumes for removal to meet budgeted synthetic crude oil production. This planning facilitates efficient allocation of mining equipment and resources. The feed grade to the Extraction Plant is monitored at various points along the delivery system.

Jan 1, 1984

By David J. Roha

"The harsh environment of the Carbothermic Aluminum process makes necessary numerical modeling as a means of process visualization and understanding. A brief survey of the various numerical models, with emphasis on CFD, applied in the development of the process is presented.IntroductionThe environment of the Alcoa Carbothermic reactor is necessarily a harsh one, with temperatures approaching 2100 °C and plenty of reactive dust and vapors. As such, it is difficult to directly observe what is actually taking place. Thermocouples can last for a few minutes but are eventually destroyed. The openings to optical pyrometers become occluded with dust and condensation. Graphite sheathing embrittles, reacts away or becomes clogged with condensate. Dip-samples on steel rods are routinely taken, but their interpretation is often unclear.Those measurements that can be reliably taken are invaluable, but often do not provide a complete picture. Therefore from the very inception of the project both physical and computer based models have played an important role. Modeling provides an intuitive understanding of the processes that might be taking place and in very many cases approach quantitative prediction. I will briefly touch upon computer-based modeling performed at Alcoa over 12 years of the Carbothermic project, with special emphasis on CFD. The explanation of physical models is perhaps best left for those with the greatest familiarity with them"

Jan 1, 2012

By P. K. Kaiser, M. Cai

When designing an efficient and effective support system for burst-prone ground, it necessary to select the most appropriate, i.e., the ‘right’ support components, including areal and reinforcement components. For this paper, it is assumed that the areal support is not the weakest link and the support performance is controlled by the rock reinforcement and holding components (bolts). We discuss the loading modes of rockbolts under static and dynamic loadings and analyze published data from laboratory and field tests. The mechanisms of energy absorption of dynamic rockbolts are presented and rockbolts are categorized based on factors such as energy absorption capacity, energy absorption rate, direct and indirect energy absorption capacities, rock mass bulking or displacement control, and shearing resistance capacity. Guidelines for selecting the ‘right’ rockbolts to build an effective rock support system for burst-prone ground are provided.

Apr 26, 2022

By Gerald W. Elger

This report compares the quality of zirconium metal prepared by batch reduction of zirconium tetrachloride by (1) sodium, (2) magnesium, and (3) mixtures of sodium and magnesium. Criteria for quality are based on chemical analyses and hardness testing of zirconium arc-melted from sponge. The best quality zirconium with respect to low oxygen content and hardness numbers was prepared by reaction of zirconium tetrachloride with a mixture of sodium and magnesium. It was found that this reaction could be successfully carried out by two methods: (1) addition of sodium and magnesium before the initial reaction and (2) periodic injection of sodium during reaction of zirconium tetrachloride with magnesium. The largest quantity of metal was found to be recovered from experiments in which a mixture of sodium and magnesium was used. Magnesium appeared to be a better reductant than sodium because magnesium-reduced zirconium contained less oxygen and exhibited lower hardness numbers than sodium-reduced metal.

Jan 1, 1962

By Karl Dufresne

Blasting in geothermally high temperature ground and/or extremely reactive ground is an increasing common challenge for surface and underground mines. Many current PETN based non-electric and electronic detonators have manufacturer published in-hole temperature limits ranging from 55°C to 65°C (131°F to 150°F). When confronting blasthole temperatures above the manufacturer published limits, operations may request site-specific guidance and qualification for use. The advised safe loading window for in-hole PETN based detonators is often too short to be practicable for production blasting. To overcome limitations of PETN based initiation systems, surface mines with high temperature ground and/or reactive ground are known to load blastholes with a qualified high temperature bulk emulsion that are top primed with a cartridge of temperature qualified detonator sensitive emulsion plus an RDX detonating cord downline. As there is no in-hole delay detonator in this system, blasthole timing is accomplished with surface delays. Although this system is safe, top priming and surface delaying does influence floor quality and top size fragmentation, and safe loading windows times reduce blast block size and increase blasting frequency. A mining company with a site characterized by geothermally high temperature ground plus highly reactive ground employed a blasting system like the one described above. The site desires to improve blasting performance by moving to an in-hole delay initiation system that can withstand the site ground conditions. At the request of the mining house, DynaEnergetics developed an electronic initiation system for application in geothermally high temperature ground and/or extremely reactive ground conditions. The DynaEnergetics IGNEO high temperature electronic initiation system is rated for in-hole use in ground up to 150C (302°F) for 48 hours. The detonator consists of a high strength detonator with an HMX base charge and thermally resistant downline. To make up a primer, the detonator is inserted into a booster charge assembly that is fitted with a small HMX shape charge. This high energy primer is designed to be compatible and reliable for firing bulk emulsions, including those with high percentages of urea inhibition to combat reactive ground. Up to 1000 detonators may be programmed in 1ms increments up to 1500ms. The system is controlled by a digital firing panel that can be used with either a wired or wireless trigger.  The system enables high temperature and/or reactive ground sites to utilize in-hole delay initiation and realize the associated performance benefits. Conclusions and Future Work 1] The HMX based electronic initiation system permits bottom in-hole delaying in ground temperatures above 80°C (175°F). As compared to top priming and surface delaying, in-hole bottom delaying is known to improve floor quality, muckpile fragmentation uniformity and reduce oversize. 2] Field evaluation of the HMX initiation system at the Lihir Mine is continuing. 3] Work on the next generation of the HMX initiation system is underway and will bring with it expanded application range and flexibility. 

Oct 1, 2024

By John F. Wiggert

DURING the early years of Homestake operations, shaft signaling from the cage tenders to the hoisting engineers was done by mechanical means. Small steel cables or jointed steel rods were suspended in the shaft compartments and counterbalanced with weights or springs. These cables or rod strings were connected to the mechanically operated gongs at the engineers' stations by means of bell cranks and steel wires. The system was simple and economical and served the purpose well until the mine reached a depth of 1000 ft., then the system became slow and cumbersome and required a considerable amount of muscular effort to operate it with much speed, because of the inertia of the heavy moving parts. The mechanical signaling was superseded by a simple electrical system consisting of a single pair of wires in steel conduit for each shaft compartment. In the shaft at each station a pull switch was connected to the wires. The switches were operated by means of bell cords, which extended from station to station. This electrical system was a great improvement over the mechanical one, but it had one serious drawback, which also applied to the older system; namely, the engineer did not know where a signal originated. Later on this signaling was improved to overcome this drawback, and to give the engineer a positive indication of a signal's origin. In this system a separate return wire from each pull switch is carried to an annunciator at the engineer's station, where it indicates the signal's origin. While the annunciator system used by Homestake is very safe and reliable, it has the inherent drawback of all wire-connected systems in that it is impossible to send a signal from a moving cage. A number of years ago Homestake became interested in the possibility of using some sort of radio transmission for shaft signaling. The company did much experimental work with purely radio signal transmission, but no practical way was discovered to use radio transmission in a mine shaft for signaling to or from a cage. Therefore, all efforts were directed to devising a practical way of using the hoisting rope as part of the circuit. It was realized that the return circuit from the rope would need to be through electrostatic coupling between the cage and the earth or ground sides of the shaft, because the guides would not always be wet enough to make possible good electrical contact between the cage and earth, therefore relatively high-frequency alternating current was chosen as the medium of transmission. Soon a practical system was developed for transmitting an electric current from a moving cage over an electric circuit of which the hoisting rope was a part. A high-frequency electric current is used as a carrier to transmit the signals or mes-

Jan 1, 1941

The earth is a planet limited in size and limited in total resources. For the forseeable future, it is the only available habitat for mankind. Therefore, it follows that the more we know about our planet the better we can utilize its space and its resources for our well-being now and in the future. But, to accomplish this, we need reliable basic information. Geosciences provide such information. Recently, Dr. M. King Hubbert took note of the important effect of the geosciences on society, on how we think, and how we live. In the first century of modern geology, 1780- 1880, the influence of geology was primarily on how we think, i.e. changing our concept of the earth from one with a short catastrophic history to one that developed gradually over enormous spans of time. In the second century, 1880-1980, the emphasis was on how we live, on expanding the knowledge base so that we could more easily find and utilize the earth's resources. Now, in the third century, i.e. from 1980 towards the year 2000 and beyond, we should concentrate on both how we think and how we live; i.e. how we can better estimate potential global' resources and how we can manage these resources for maximum benefit to mankind. Like other sciences, the geosciences build upon what has already been done. Progress is achieved by using the thoughts, measurements, and observations of past workers, adding to these the insights from new experiments and from new concepts. Geology has its own methodology and approaches; but more than most sciences, it calls also upon the tools of physics, chemistry, mathematics, engineering, and biology to help solve its problems. Today's increasing population, increasing industrialization, and increasing complexity of modern society demand more detailed geoscience information so as to better use the land, reduce geological hazards, provide an inventory of resources, facilitate waste disposal, and prepare for long-term effects such as changes in climate and sea level.

Jan 1, 1986

By Klaydison Silva, Maurício Curi Segato, Elves Matiolo, Neymayer Pereira Lima

Flotation is the main concentration process, has been applied with sucess for the removal of quartz on the iron ore industry aiming high quality concentrates. limiting the top size close to 0,300mm and the removal of slimes are fundamental for the efficiency of reverse flotation of quartz. The high consumption of reagents, leading to insufficient particle coverage, and increased foam stability, leading to the difficulty of removal of quartz particles, are the main deleterious effects of the presence of slimes. Recent characterization studies, together with the development of new collector of linear chain, allowed the obtaining of concentrate with SiO2 contents close to 3% with 94% of metallurgical recovery, based on pilot tests carried out on a sample flotation column of the Quadrilátero Ferrífero.

Oct 3, 2019

By G. E. McElroy

This report discusses the construction and use of an all-pressure psychrometric chart in which the requirements of simplicity of appearance and absolute accuracy have been waived, to a certain extent, to provide for the rapid determination of psychrometric data and for the rapid solution of air-conditioning problems of major interest to the mining industry. Many mines in which air-conditioning problems are important are situated at elevations far above sea level and embrace great differences in elevation - in excess of 8,000 feet in certain mines - throughout their airflow circuits. Under these conditions, the effects of variations in the pressure of the atmosphere upon the physical properties of the mixture of air and water vapor of which it is composed are considerable and should be taken into account in the solution of problems. The simple types of psychrometric charts in common use, such as the Carrier, Bulkeley, Hill, and Goff (American Society of Heating and Ventilating Engineers Guide), are not generally suitable, in that they are drawn for a single barometric pressure - 29.92 inches mercury.

Dec 1, 1947

By Marta Polgari, Eva Surova, Bohumil Molak

Abstract -The Ûrkút rhodochrosite deposit and Branisko Mn showings (rancieite, manganiferous calcite), located in Lower Jurassic marine sedimentary rocks with black shale, were studied by organic­ geochemical methods. Both depositionallocalities were affected by the Lower Jurassic Toarcian anoxic event. Ûrkút shales are rich in organic matter (av. 2.94 wt% total organic carbon), the composition of which indicates derivation mainly from marine sources, with some terrigenous component. The shales matured in a bacterially active environment under reducing conditions of diagenesis-catagenesis. Branisko shales (?0.2 wt% TOC) with lenses of Mn oxide ore were weakly metamorphosed and their organic matter thermally degraded. The model for Mn carbonate ore formation envisages reaction of Mn derived from sediments, with carbonate generated by a bacterially mediated process of decom­ position of organic matter that also involved Mn reduction.

Jan 1, 1992

By D. C. Holloway

Ceramic projectiles made from 94% to 99% alumina with a nominal mass of 3.1 gms were fired into granite blocks. The average compressive strength of the ceramic was 800 MPa and that of the rock was 135 MPa. Flat, ogive, conical and pyramidal nose shapes were evaluated at velocities ranging from 450 to 1400 m/sec. It was found that the conical and pyramidal nose shapes at the higher velocities did a significant amount of damage to the rock. On the average, they removed 10 5mm3 of rock and were six and ten times better than the flat and ogive nose shapes. It was also observed that increases in volume occur in discrete steps. This process is highly dependent on the ability of the projectile to penetrate the rock.

Jan 1, 1984

By D. François-Bongareon

"In previous publications by the author, significant advances and generalizations of the theory of sampling of broken ores, prompted and confirmed by experimental results, have been presented. This paper shows how to implement these theoretical results in practice. The models to be used are reviewed, with a description of the various sampling parameters involved. Then the methodology for the experimental assessment of those parameters, including segregation factors, is described in simple and practical terms, along with the use of handy sampling protocol charts. Finally, the particularly important case of processing data from a sample-tree experiment is detailed, and examples of applications covering all situations and types of experiments are provided.IntroductionThe reliability of a sample of crushed material , i.e. the expected (average) deviation between its true grade and the true grade of the lot it comes from, mostly depends upon six factors:• the size (mass) of the sample (and to a minor extent, for small lots, the size of the lot);• the size of the rock particles (degree of comminution)• the nature of the mineralization at microscopic scale (i.e., within even the smallest particles);• the geological nature of the mineralization and mineral of interest;• the grade of the lot in the mineral of interest; and• in some cases, the state of segregation of the lot.In practice, one should first disregard segregation problems, and assess sample variability in the segregation-free case. Once the numerical parameters governing this variability have been assessed, then segregation factors can be assessed in turn. In the case of laboratory standard sample preparation procedures, segregation can usually be disregarded altogether."

Jan 1, 1993

By G N. Phillips

Global annual gold production has been remarkably constant over the last decade at ~2500 t/a3. The major producers today are China (annual production over 350 t and rising), Australia (250 t), USA (240 t), Russia (200 t) and South Africa (190 t and falling); these figures are representative of recent years but approximate. Demand from jewellery, investment, industrial and dental uses has been in excess of mine production for the last decade, by approximately 1000 t/a.Ongoing exploration is the life-blood for gold mining, and more so than for many other metals. Explorers consider sovereign risk, security, labour costs, commercial terms, land availability and inherent geologic prospectivity to determine where to focus their activities. Exploration success over the last decade has been shared by established major producers like Australia, Canada and USA, several countries in West Africa, and many parts of the Pacific margin. Although gold-only deposits have dominated world gold production historically, the gold-plus types, especially copper-gold, are becoming more important.Australia experienced a major period of exploration success from 1979 that has led to annual gold production rising from 17 t in 1979 to 250 - 300 t/a recently. Today, Australia has economic demonstrated resources of over 9000 t Au, which has risen progressively from 220 t in 1979. The majority of production has come from gold-only deposits in the Yilgarn craton in the southern half of Western Australia, but there are a few large Proterozoic deposits in central Australia including Olympic Dam, Telfer and Starra, which are mostly gold-plus types with copper and gold. Large goldfields in the younger host rocks of eastern Australia include the gold-only deposits of Victoria and North Queensland, and gold-plus deposits of New South Wales.CITATION:Phillips, G N, 2013. Australian and global setting for gold in 2013, in Proceedings World Gold 2013 , pp 15-22 (The Australasian Institute of Mining and Metallurgy: Melbourne).

Sep 26, 2013

By D David

Geometallurgy is often a misunderstood and poorly defined concept. The first thing the paper will attempt is to provide a definition of geometallurgy. Ultimately this paper has been written to provide guidance to geologists, mining engineers and processing professionals as to what geometallurgy means in the crucial early phases of a potential mining project between the time of discovery and the time of commencing construction, should this occur. The paper covers the options available for conducting a geometallurgical study of a resource or orebody, appropriate to the level of definition required in the projectÆs development cycle. The paper will then describe how the geometallurgical information generated is subsequently used in calculations, planning and preparation of reports designed to inform and reassure stakeholders, such as the market. Ultimately in a successful project, appropriate options adopted in the development phase will form the basis of an ongoing geometallurgical program that links the major site disciplines for the good of the operation.CITATION:David, D, 2013. Geometallurgical guidelines for miners, geologists and process engineers - discovery to design, in Proceedings The Second AusIMM International Geometallurgy Conference (GeoMet) 2013 , pp 129-132 (The Australasian Institute of Mining and Metallurgy: Melbourne).

Sep 29, 2013

By Lumley G. I, Hayes H

Non-intrusive methods for the reliable determination of dragline bucket and rigging performance have been achieved using physical modelling. Modelling offers a logical first step towards developing mathematical simulation models. The process of physical modelling has been applied successfully to predict dragline bucket performance and capacity as well as to demonstrate the effect of varying dump rope length on performance. ACIRL's Surface Miming Group has used physical modelling to carry out dragline bucket sizing for a new high productivity bucket and compared performance with Throng Coal's existing dragline bucket. The predicted bucket performance has since been confirmed in the field using dragline monitoring techniques.

Jan 1, 1992

By J Hartnett, B Tarrant, A Rayner, D O’Toole, P Davies

Since 2009, the Northern Territory and Australian governments have been working under a national partnership arrangement to inform a rehabilitation plan for the former Rum Jungle uranium mine. Part of the rehabilitation strategy is to backfill a flooded former pit (Pit), which extends down to 100m below the current pit lake surface and was historically partially backfilled with uranium tailings. It is proposed to utilise the remaining pit volume below water level to sub-aqueously store Potentially Acid Forming (PAF-I) waste rock which currently occupies large stockpiles across the site. The rehabilitation design and planning process undertaken to develop a strategy commensurate to project objectives and construction constraints involved the establishment of key constraints derived from the analysis of historic data sources and preliminary design efforts. Tabled strategies were balanced against dependent project tasks and project objectives, especially surrounding minimising disturbance of highly contaminated materials within the Pit. Ideas were developed in conjunction with industry input and review of case histories to develop a remediation solution that is constructible within the project timeframe and constraints.

Jul 1, 2021