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By D. Eugene Rannels, Sarah E. Dunsmore, Cara Martinez-Williams, Yu-Chen Lee

"Dunsmore, Sarah E., Yu-Chen Lee, Cara Martinez Williams, and D. Eugene Rannels. Synthesis of fibronectin and laminin by type II pulmonary epithelial cells. Am. J. Physiol. 270 (Lung Cell. Mol. Physiol. 14): L215-L223, 1996.Previous investigations demonstrated that type II pulmonary epithelial cells regulate extracellular matrix deposition as a function of time in primary culture. In those studies, the matrix fraction was analyzed as a whole. The present work focused on two components of the type II cell matrix, fibronectin and laminin. These glycoproteins have differing effects on differentiation of type II cells in primary culture. Fibronectin synthesis was quantitated between day 1 and day 6 in the cells, matrix, and medium; laminin synthesis was quantitated only in the cells. Although total fibronectin synthesis was regulated as a function of time in culture, reaching its greatest value on day 2, the average proportion of newly synthesized fibronectin in the cells (35%), medium (50%), and matrix (15%) remained constant over a 6-day interval. Between day 2 and day 6, the relative abundance of fibronectin messenger RNA increased 6.5-fold. Rates of cellular laminin synthesis did not vary with time in culture. These results support a role for differential regulation of fibronectin and laminin synthesis to determine the composition of the type II cell extracellular matrix. INTERACTIONS BETWEEN THE pulmonary epithelium and alveolar basement membrane may play a role in the physiology and pathophysiology of the lung. Pulmonary epithelial cells and the alveolar basement membrane form one component of the blood-gas diffusion barrier. Integrity of this barrier is crucial to normal lung function. Specific domains of alveolar basement membrane components have been proposed to determine localization of type I and type II pulmonary epithelial cells during lung growth and development, as well as during repair of the alveolar surface after injury (13). In the injured lung, the extent of damage to the epithelium and the underlying basement membrane is thought to be a key factor to determine subsequent repair or fibrotic scarring (3)."

Jan 1, 1998

By J. Bruce Clemmer

[Gypsum is one of the mo .. t iJf.l)ortant nonmp.tal1.ic T!1inerals, as is indicat-? ed by the fact that tlle Uni ted states cO!1sUl:Ied p, roximn..tely 3,500,000 tons of natura.l and calcinecl e::,j;-psum in 1937. The b\.'.ilr:.in.; traces \"fe.ro the largest users and required 2,520,000 tons of calcine for the r-roductiop. of plaster,]

Jan 1, 1941

By L. J. E. Hofer

THIS BULLETIN analyzes and summarizes research at the Bureau of Mines dealing with the preparation, properties, and reactions of iron carbides in the period 1948-60, part of which was sponsored by Wright Air Development Laboratories. The objective was to develop better catalysts for the synthesis of methane and higher hydrocarbons from hydrogen and carbon monoxide. The investigations resulted in the first adequate characterization of epsilon iron carbide, which later proved to be an important intermediate in the tempering of martensite in steel. At temperatures near 170° C, the carbon in carbon monoxide reacts nearly quantitatively with finely divided alpha iron to form an iron carbide in which the metal atoms occupy the positions of the close packed hexagonal arrangement with lattice parameters of ao=2.754 A and co=4.349 A. The carbide has a composition within 2 atomic percent of that required for the formula Fe2C, a Curie point of about 370° C, a specific magnetization of 160.4 ergs per gauss-gram Fe at 50° C, and a ferromagnetic moment of 1.70 Bohr magnetons. Epsilon iron carbide can be converted to chi iron carbide by thermal treatment at 343° C for about 70 hours. The chi iron carbide so formed has a Curie point of 247° C, a specific magnetization of 142.5 ergs per gauss-gram Fe at 50° C, a ferromagnetic moment of 1.72 Bohr magnetons per iron atom, and a paramagnetic moment of 5.5 Bohr rnagnetons per iron atom. Direct synthesis of this carbide from carbon monoxide at 240° C indicates a composition within 7 atomic percent of that required for Fe2C. Chi iron carbide can be converted to cementite at 550° C in about 315 minutes. The theta iron carbide so prepared has a Curie point of 210° C, a specific magnetization of 147.3 ergs per gauss gram Fe at 50° C, a ferromagnetic moment of 1.72 Bohr magnetons per iron atom, and a paramagnetic moment of 3.9 Bohr magnetons per iron atom. Pure chi iron carbide reacts to form theta iron carbide by the elimination of free carbon. In the presence of an excess of free iron in intimate contact with the carbide, chi iron carbide reacts with the free iron to form theta iron carbide. The second reaction proceeds at an appreciable rate at 320° C and can be used to snythesize finely divided theta iron carbide with no free-carbon impurity at low temperatures. The ease of the reaction in the presence of free iron suggests that chi iron carbide is an intermediate in the tempering of epsilon iron carbide to theta iron carbide as it proceeds in steels. Experiments on carbon steel show that the magnetic moment of the iron atoms in martensite is about 2.2 Bohr magnetons per atom, a value approximately the same as that of the iron atoms in alpha iron. The Curie points of epsilon iron carbide, chi iron carbide, and theta iron carbide were found -in various specimens of tempered steel to be 10° to 20° C lower than normal values. This shift is probably the result of manganese in solid solution. Preparations of various compositions of epsilon iron carbonitrides show many effects of extensive isomorphism between epsilon iron carbide and epsilon iron nitride. The action of carbon monoxide on finely divided alpha iron at 400° C results in free carbon deposits containing filaments about 0.1 micron in diameter and several times as long. The filaments are characterized by nuclei of dense material located midway from each end of the filament. Although carbiding to near completion at 240° C over periods of about 300 hours produces a preparation containing no appreciable percentage of epsilon iron carbide, very brief periods of carbiding of the order of a minute result in the formation of detectable epsilon iron carbide even at temperatures as high as 325° C. The data indicate that epsilon iron carbide is an intermediate in the formation of chi iron carbide during its formation from carbon monoxide in the gas phase. Attempts to convert cementite to chi iron carbide by cold work increased the Curie point but did not change the X-ray powder diffraction pattern.

Jan 1, 1966

A computer system for calculating the illumination on coal mine surfaces due to machine-mounted lights is described. Utilizing numerical models of mining machinery and measured data on luminaire output characteristics, the program computes the ft-candle levels incident on the mine entry surfaces for any desired machine/luminaire/ entry configuration. Shadowing effects of the machine are taken into account. Results are provided at 2 ft. intervals on the face, left and right walls, floor and roof. The system operates, interactively from a Tektronix 4014 graphics terminal which handles all input/output functions. The software is installed on a Cyber 74 computer that communicates with the terminal via telephone line.

Jan 1, 1978

According to industry representatives, U.S. producers were listing unalloyed 95.5 percent aluminum ingot in October at 53-57.5 cents per pound, but reportedly much is being priced at 53 cents. New York dealers raised their October positions by about 3 cents to 56-56.5 cents, mainly to cover spot supply shortages. London Metal Exchange 3-month forward contracts traded up in October from 52.3 to 57.3 cents per pound and closed at 56.4 cents. ASBESTOS The Jaquays Asbestos Corp. has announced the imminent closure of its mine and mill in Globe, Arizona. This is the last asbestos producer in the State having operated continuously, except during the early thirties, since 1914. Cost of compliance with environmental regulations was given as the reason for closure.

Jan 1, 1978

These proceedings consist of papers presented at two Bureau of Mines Technology Transfer Seminars in early 1980 for the purpose of disseminating recent advances in mining technology related to surface coal mining reclamation.

Jan 1, 1980

By J. F. McCoy

The quantitative determination of the mass rate of flow of methane in an underground airway is calculated as the product of the methane concentration and the air flow rate. Velocities are taken at several points and then averaged over the airway cross section to determine the total volume flow. Errors in velocity measurement thereby result in errors in total volume flow as well as the mass flow rate of methane. The purpose of this program was to evaluate existing instrumentation for measuring air velocities in the speed range under 2000 feet per minute; to evaluate the method for determining total air volume flow from the velocity measurements; to evaluate new techniques which may be applied to measuring air velocities; and to design a prototype instrument which represents the best technique based on the evaluation. The instrument should be: a. portable b. self-contained c. insensitive to dust, moisture and temperature changes d. safe for use in gassy mines

Jan 1, 1972

By H. C. Miller

"Introduction**The progress of the ""Safety First"" movement in the oil fields of California during the past few years has been remarkably rapid. It has been generally concede by those who have learned to value the life and limbs of their employees, that safety is essential to efficiency and no company that has a high accident rate can be considered an efficient organization. Accidents have a destructive effect on the morale of any body of workers and cause disorganization and delays.The increasing danger to life and limb involved in the drilling for and the production of oil and gas, has become so great that it is clearly evident that everything possible must be done to keep it within the narrowest possible limits.There is a tendency toward carelessness, especially by men who are employed in hazardous occupations. This is brought about by the familiarity of the risk under which they are working and in no industry is this more forcibly exemplified than in the oil fields. Men have performed the same or similar duties for many years and have worked around similar hazards and unprotected machinery until many have can entire disregard for the dangers surrounding then. Very often familiarity with a hazard occasions a contempt for that hazard which only too often results disastrously."

Dec 1, 1923

By Michael Sokaski

The Cliff Springs prospect in the northern part of the Slate Range Wilderness Study Area (WSA) contains only minor amounts of gold and silver. Clay near this prospect contains insufficient aluminum to be of economic interest, although alunite claims are recorded in the vicinity. Mineralized rock at the Crescent Mine adjacent to the WSA contains gold, silver and lead occurrences. The host rock may be present in the extreme southwestern part of the WSA, which is covered by alluvium. Substantial sand and gravel deposits are present but these occurrences are remote from markets. Much of the USA is underlain by volcanic rocks and alluvium and consequently the mineral resource potential there remains unknown.

Jan 1, 1983

By Ronald T. Mayerle

In-1992, the U.S. Bureau of Mines conducted a mineral investigation of the Anderson Mountain study area, including RARE II area 4-942, in Lemhi County, Idaho. The 7,340-ha study area lies within the Salmon National Forest about one kilometer north of the old mining town of Gibbonsville (pop.: 100). The eastern boundary of the study area is formed by the crest of the Bitterroot Range. The crest also serves as the continental Divide, and as the border between Idaho and Montana. The study area lies within the Gibbonsville Mining District, an important past producer of gold from lode and placer deposits. Since the 1870's, several hundred claims for both types have been located in the study area. Thirty-six current (1992) lode claims and two patented claim groups (one lode and one placer) are wholly or partially in the study area. No placer claims are current. In all, twenty-seven lode and five placer properties in and adjacent to the study area were investigated. Workings on the properties included 2 caved shafts; 36 caved adits; 8 open adits; 120 small pits, cuts, and trenches; and 4 large dozed cuts.

Jan 1, 1993

By G. L. Oldright

This paper is the fourth of a series of preliminary papers on smelting in the lead blast furnace.4 The objects of this investigation are to determine the conditions obtaining within the blast furnace by direct experimentation and to correlate these conditions with operating factors, furnace behavior, and metallurgical losses. ACKNOWLEDGMENTS The authors wish to express their appreciation to the management of the International Smelting Co. at Tooele, Utah, for their whole-hearted cooperation in this investigation.

Jan 1, 1929

By W. W. Adams

The extent to which coal mines have installed various types of haulage systems and mining machines is a subject about which there is little definite information available in convenient form for the country as a whole . A few State mine inspectors include in their annual reports such information for their respective States , but uniform data for the United States have not until recently been compiled . Several years ago the Bureau of Mines compiled from one of the standard mining directories * a statement showing the kinds of machines and haulage used in coal mines . The first statement was prepared from the 1918 edition of the directory in which detailed descriptions of coal mines were given . The information presumably related to the calendar year 1917. Similar statements have been compiled from the directories for 1919 , 1920 , and 1922 , the statement for 1921 having been omitted because the directory for that year did not become available . The latest statement is given below and is based upon the directory for 1922. It relates to conditions prevailing in 1921 , and covers a total of 7,088 coal mines . Of these , 5,064 mines . or more than 71 per cent , were using animal haulage . As compared with the total number of all classes of mines , those in the animal - haul age group constituted 71.4 per cent , the percentage having remained practically stationary during the past four years , although the actual number of mines in the group has increased . Rope haulage was reported by 1,066 mines , or 15 per cent of the total , representing a larger number of mines than in 1918 , but a decrease of 2 in the percentage for the group as compared with all classes of mines . Electric haulage was reported by 3,274 mines (46.2 per cent ) , and the number of motors in use was 11,265 . The percentage of mines in this class has not changed materially, but the actual number of mines has shown a gain of about 900 during the past four years . Compressed-air locomotives have not increased either in actual or relative number , the percentage for the past year being but 1.2 . The number of mines using storage- battery locomotives has increased from 3.6 per cent of the total shown four years ago , to 9.8 per cent for last year, the latest figures showing 693 mines with 1,428

May 1, 1922

By Mark S. Sanders

This report discusses the development and testing of prototype gloves for underground mining work. An analysis of HSAC hand-finger injuries revealed three high-risk jobs: laborer, mechanic, and roof bolter. Laboratory tests of dexterity and protection were performed using six off-the-shelf gloves. Two prototype gloves were developed. Both were Kevlar-cotton blend knit gloves. One had polyvinyl "Ks" screened on the palm and fingers, and a hand pad sewn into the palm. The other prototype had the palm and fingers coated with a sol id layer of polyvinyl and had no hand pad. Field tests revealed that the solid-coated gloves were preferred by workers, but that the polyvinyl melted when working with hot drill steels.

Jan 1, 1985

By Stephenson. E. L.

"INTRODUCTION In the spring of 1942 a series of magnetometer surveys on deposits of black sand underlying Pleistocene raised marine terraces along the coast of southwestern Oregon was nada by the Division of Geophysical Exploration of the Federal Bureau of Mines in cooperation with the Oregon Department of Geology and Mineral Industries. A few preliminary tests had been made in the same area in May 1940 and December 1941.The sands contain fine gold and metals of the platinum group, and, beginning in 1852, extensive, but spasmodic mining and exploration have been done for these precious metals. There are many old placer, mines and prospects, although for the most part the yield of the metals has been small. The sands also contain other minerals of potential value, including ilmenite, magnetite, garnet, zircon, and particularly chromite, and the wartime demand for domestic chromite resulted in extensive testing and development of the known deposits. The purpose of the magnetometer surveys was to determine the efficacy of, magnetic methods in tracing and outlining these known deposits and in prospecting for new ones. The field work was done between March 17 and May 29, 1942, by the author assisted by W.W. Paulsen of the Oregon Department of Geology and Mineral Industries."

Jun 1, 1945

By D. E. Van Dillen

Three-dimensional structural analyses of three instrumented areas of a deep, longwall coal mine have been performed using the finite element code BMINES. The three Instrumented areas include two single-entry portions and one double-entry portion of the Sunnyside No. 1 Mine, Sunnyside, Utah. The finite element models simulated the sequence of excavation in each test area: the advance of the entry, installation of structural supports, retreat of the longwall, caving behind the longwall, and accumulation and loading of the gob. The structural supports considered in these finite element models include rock bolts, wood cribs, concrete cribs, steel arch sets, and chocks. Mechanical simulation of the geologic environment is achieved through elastic/ perfectly plastic material models employing anisotropy to represent finely layered regions of the medium. The results of these calculations are com-pared with the instrumentation readings from the mine. These measurements include closures, crib loads, rock-bolt forces, and stress growth.

Jan 1, 1978

By Michael S. Contratto, Dave Marshall, Tom Brodersen

The European Union (EU) completed a new directive 2002/44/EC1 called the Physical Agents Directive (PAD) that establishes action and limit values for hand-arm and whole body vibrations. The directive specifies that: “…workers shall not be exposed above the exposure ‘limit value’.” 1 and “…once the exposure action values … are exceeded, the employer shall establish and implement a programme of technical and/or organisational measures intended to reduce to a minimum exposure to mechanical vibration and the attendant risks…” 1 The PAD limit value is effective for new machines starting July 6, 2007 and for used machines by at least July 6, 2010. These requirements apply to the users of machines, but machine manufacturers will be challenged to provide machines and information to help the users comply with the directive. Caterpillar manufactures machines with the goal of enabling our customers to comply with all regulations dealing with health and safety. Caterpillar designs all of our machines to provide a safe, comfortable and productive work environment. This study was to determine if seat suspensions could provide a reduction in the vibration environment experienced by operators of Caterpillar mid sized (<50,000KG) Track Type Tractors Methods Seat manufacturers were asked to provide seat suspensions that provide improved isolation over and above current seat suspension. Each supplier was provided with ride profiles and was asked to demonstrate the vibration reduction on a shaker table. Two suppliers provided suspensions that were compared with the current seat suspension in a field study. Three full factorial experiments were conducted. The first experiment was to evaluate overall suspension performance for four operations. The second experiment was to determine the benefit of the adjustable vertical damper at three different levels and the third experiment was to determine the effect of the fore/aft and side/side isolators. Six operators were used for the study. Acceleration was measured at the seat base and at the operator seat pad. Both the transfer function and the ISO 2631 RMS ride values were used to determine the seat suspension’s effectiveness of isolating the operator from vibration. A structured questionnaire was used to determine the operators’ subjective assessment of the seat suspensions. Results There was significant operator-to-operator variability in the vertical direction (>35%), however there was little variability in the fore/aft and side/side direction based on seat base

Jan 6, 2006

By Sabri Ergun

NEW theoretical data are presented for the intensity of X-rays diffracted from randomly oriented aromatic and alicyclic molecules and diamondlike structures such as are found in coals, cokes, and carbonaceous materials. Data have been computed using the Debye interference function. Computations for the smaller molecules have been made with the Univac 1204 computer: those for large structures, with either the IBM 704 or Bendix G-20 computer. A brief theoretical introduction of the Dobye interference function is given, and an outline is made of the treatment of experimental data so that the experimental interference function can be obtained.

Jan 1, 1965

By Charles B. Carpenter

In general terminology, the West Texas Permian Basin companies the area south of the Texas Panhandle and west of the Bend Arch or Central Basin region. It is outlined more definitely by geologists however, as that area underlain by the south half of the Permian Salt Basin4/ and includes Scurry, Mitchell, Sterling, Howard, Glasscock, Reagan, Crockett, Upton, Midland, Martin, Gaines, Andrews, rotor, Crane, Pecos, Ward, Winkler, and Loving Counties in Texas, and.. Lea and Eddy Counties in New Mexico. The oil fields of the area, of which more than 70 have been discovered, are shown in fire 1. Approximately 4,200 producing oil wells have been drilled in these fields. Oil has been produced from limestones and dolomites of Permian age in most of the fields in the West Texas Permian Basin. Some of the fields produced oil from sandstone beds above the limestone, and in two fields production has been found below the limestone in formations of Ordovician age.

Jan 1, 1936

By Charles B. Carpenter

In general terminology, the West Texas Permian Basin comprises the area south of the Texas Panhandle and west of the Bend Arch or Central Basin region. It is outlined mere definitely by geologists, however, as that area underlain by the south half of the Permian Salt Basin4/ and includes Scurry, Mitchell, Sterling, Howard, Glasscock, Reagan, Crockett, Upton, Midland, Martin, Gaines, Andrews, Ector, Crane, Pecos, Ward, Winkler, and Loving Counties in Texas, and Lea and Eddy Counties in New Mexico. The oil fields of the area, of which more than 70 have been discovered, are shown in fire 1. Approximately 4,200 producing oil wells have been drilled in these fields. Oil has been produced from limestones and dolomites of Permian age in most of the fields in the West Texas Permian Basin. Some of the fields produced oil from sandstone beds above the limestone, and in two fields production has been found below the limestone in formations of Ordovician age.

Jan 1, 1936

By G. L. Oldright

The studies previously made on Smelting in the Lead Blast Furnace have dealt with the custom smelter of the International Smelting Co. at Tooele, Utah, and on the smelter of the Bunker Hill & Sullivan Mining & Smelting Co. at Kellogg, Idaho. The International plant may be considered representative of the traditional custom smelter. The lead smelter of the future seemingly will have to treat increasingly richer lead charges. This feature was then stressed in describing the Bunker Hill plant.

Jan 1, 1934