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By Nelson R. Shaffer

Biotechnology has become a household word of the nineties, and it is expected to become as important in the next century as the computer is in the present. Numerous books and articles portray biotechnology developments as nothing less than a scientific revolution. Almost everywhere one looks new biotechnical breakthroughs are being reported that offer almost limitless opportunities to harness the force of living things to produce materials and manipulate their properties. Biotechnology has been broadly defined as any applications of biological organisms, systems, or processes to manufacturing and service industries. This seemingly new technology is, in fact, one of mankind's oldest scientific activities (Table l), which has been recently revolutionized by techniques of genetic engineering that arose out of basic research in biology, biochemistry, genetics, and information sciences. From fields as old as agriculture and medicine to those as new as monoclonal anti-bodies, transgenic plants, or biocomputers are encompassed by biotechnology. Like most human endeavors, industrial minerals play critical roles in biotechnology. In addition biotechnology holds real potential to improve extraction and beneficiation of certain industrial minerals themselves. BIOTECHNOLOGY OVERVIEW Companies using established biotechnical techniques make up large and diverse groups such as agriculture, chemicals, and pharmaceuticals. The massive US Pharmacopia (Anon., 1990a) provides detailed specifications for minerals used in medicines. Alumina, zirconia, apatite, and bioactive glass have seen service as implant materials (Williams, 1990) and new uses for minerals in health sciences are being actively researched. Agriculture produced $361 billion worth of food and drink during 1991 in the United States; organic chemicals, pharmaceuticals, and enzymes accounted for $68, $59, and $42 billion, respectively (Anon., 1992a). It is not possible to separate the contributions of industrial minerals to biotechnical products, but they represent a very large and rapidly growing new field of uses. The new biotechnology has nearly 300 small companies, plus 15 established companies with 742 biotechnology-related firms (Dibner, 1991b). Revenues exceeded $2 billion in 1990 and are expected to grow to $50 billion by 2000 (Anon., 1992c), with worldwide sales exceeding $100 billion (Burrill and Roberts, 1992). Federal research amounted to $3.4 billion in 1990 (Anon., 1992b). The United States is the world leader in biotechnology, but other countries have large, well-funded programs. Despite debate about safety, obstacles to new biotechnology products are declining (Embers, 1992, Gibbons, 1991). Fifteen biotechnology drugs valued at $1.2 billion (Thayer, 1991a) are on the market, and more than 100 are in various stages of testing (Edington, 1992). Many diagnostic tests are also in use or development (Demain, 1983, Anon., 1992). Large scale efforts to produce or transform important chemicals are also underway (Ng et al., 1983, Hinman, 1991), and research into geologic uses of biotechnology has begun. Much has been published about microbial mining, oil recovery, desulfurization, bioremediation, and other geologic aspects of biotechnology, but this chapter is the first attempt to explore interactions of biotechnology and industrial minerals. This chapter examines uses of minerals in biotechnology; how biotechnology can be used to discover, recover, and beneficiate industrial minerals; and speculates on some potential, but as yet untried uses. Definitions What exactly does the word biotechnology mean? Bud (1989) states that the first use of the term was by Karl Ereky in 1919 to cover the interaction of biology and technology, and in 1933 the term was used in Nature. After citing seven different definitions, Smith (1988) concludes that biotechnology is a series of enabling technologies involving practical applications of organisms or their subcellular components to manufacturing and service industries or to environmental management. Walker and Cox (1988) suggest a definition of "the practical applications of biological systems to the manufacturing and service industries and to the management of the environment." Primrose (1991) says that it is "the commercial exploitation of living organisms or their components." There is essentially an older broad use of the term and a new use. The US Office of Technology Assessment (Anon., 1984) uses a broad definition that includes any technique that uses living organisms (or parts of organisms) to make or modify products, to improve plants or animals, or to develop micro-organisms for specific uses. Definitions are different, but they all have several fundamental elements that include the control, management, or manipulation of living things for commercial, industrial, or useful ends. While such a definition encompasses all of agriculture in practice the "new" biotechnology is restricted to processes involving microorganisms-plant and animal cells, or enzymes. Many consider biotechnology to be recent, but it is one of our oldest technologies as evidenced by the prehistoric origin of brewing, cheese-making, and other techniques. [Table 1] gives some of the important developments in the history of biotechnology. Smith (1988) breaks down historical developments of biotechnology into four phases: 1) prehistoric with no understanding of underlying processes; 2) nonsterile processes; 3) sterile processes after 1940; and 4) genetic and recombinant DNA technology deliberate design of special organisms or processes.

Jan 1, 1994

By J. Herbst, I. Heber-Panu, Dan G. Cojocariu, E. Ene-Danalache, G. Poling

A general model which represents not only batch but also continuous flotation in multi-cell machines is presented. This model considers both the size distribution and the distribution of flotabilities in a size class for valuable mineral particles in the pulp. The general expression is shown to reduce to several previously reported models. In addition, a number of new models are found to arise for different specific assumptions concerning the flotability distribution and/or the size distribution of the particles undergoing flotation. Several of these new models are tested experimentally using laboratory-scale batch and pilot-scale continuous data. Model parameters are estimated from this data and a comparison of calculated recoveries and those experimentally determined are presented. Finally, the influence of the feed rate, aeration rate and valuable mineral content of the feed on the recovery is examined.

Jan 1, 1976

By Wen H. Su

Extensive investigation has been conducted to determine the causes of a series of roof falls occurring in a room-and-pillar working located in southern West Virginia. Underground observation, along with laboratory testings and finite element analyses were conducted to search for possible mechanisms for the roof falls. Results of the investigation have led to a better understanding of the mechanisms involved in the roof falls. Necessary modifications of mine layout and roof support plan are proposed for improving safety and profitability at the mine.

Jan 1, 1984

By Mortimer J. Richardson

Dredging can be traced to early times where it may have been derived by the Phoenicians prior to the 4th century B.C. The first tangible design drawings of a bucket ladder (BL) dredge can be found in the collections of Leonardo da Vinci (1452-1519), which he produced when he was attempting to create better methods of channel and port dredging. The perfection of the system did not commence until after the invention of the steam engine in the early 1800's; providing the impetus to progress from man-powered mud mills, horse drawn along polders or dikes in the Netherlands, England, France and Germany, to steam-driven. In the 1860's following the various gold rushes in the U.S., Australia, New Zealand, Siberia and South America, with placers in particular, efforts were begun to apply mechanization to achieve deeper digging. There is a recording of a dredge being installed to mine gold in Montana in the 1860's but did not include a processing system. Then in the 1880's in New Zealand, some practical engineers developed a system that is said to be the first bucket ladder mining (BL/M) dredge for mining gold placers. In studies of the New Zealand gold dredging experience, it is estimated that some 500 dredges were built to mine gold between the 1880's and 1942. A careful analysis of the data, however, shows that very few were profitable. The technology appeared to stagnate in the early part of the century. Two of the BL/M dredge design engineers left New

Jan 1, 1992

By J. G. Smith

Of the variables affecting the electrical properties of coal measure rocks, water content is by far the most important, This paper describes specially developed apparatus and methods of measuring electrical conductivity and permittivity at constant humidity conditions. Electrical properties variations were measured for Applachian and Illinois, U.S.A. coal 2 basin samples in the frequency range 2 X 10 to 2 X 10 Hz. Coal measure rock electrical behavior, when correlated with mechanical behavior, is potentially useful in a number of mining applications.

Jan 1, 1985

By J. E. Garlanger, R. K. Shrestha

During mining, the surficial aquifer and, in some cases, the top of the uppermost confining unit within the mined areas are excavated. Portions are removed from the area for resource recovery. Until the mined areas are reclaimed, the surrounding unmined area continues to dewater. The impact of mining and subsequent restoration of the surficial aquifer on the ground and surface water resources of the watershed affected by the mining will be described. This will be done in terms of ground water recharge, ground water levels, and base flow and runoff to surface streams. Data from actual mining situations will be used in analyses and discussion. Recommendations will be made for further research.

Jan 1, 1992

By Charles E. Robertson

As it becomes more and more apparent that our nation must place a great deal of reliance on coal as an energy source in the coming decades, prospecting for new reserves Un Missouri and other states in the Western Interior Region is increasing. As more and more of the known reserve becomes committed to existing or planned projects operators will be forced to look beyond the fringes of existing coal fields for additional reserves. Perplexing geologic problems invariably confront all prospectors and are particularly bothersome to those new to a particular area. It is the purpose of this paper to alert prospective operators to geologic problems likely to be encountered and to offer guidance in the recognition and solution of these problems. Particular emphasis is placed upon geologic structure and washouts. Other geologic problems have been discussed in a previous paper.

Jan 1, 1977

By S. D. Thompson

Several discrete-event simulation models have been developed for designing the conveying system capacities of underground coal mines. Most of these models require the use of a step function approach to mimic the loading process at each conveyor loading point. Over the years, practitioners have generally employed one of three versions of the step function approach. An important issue is how these three versions compare to each other in terms of simulated capacity requirements for belt conveyors. Another issue is how they compare to the peak capacity design. This paper addresses these issues by statistically and quantitatively comparing their simulation results. The consequences and problems associated with using each version are also discussed and summarized.

Jan 1, 1998

What is your assessment of the current state of the minerals industry? It is no understatement that domestic mining is facing a severe crisis at this time. The sharp decline in commodity prices and demand is putting a great strain on domestic and worldwide mining, causing major declines in profits and market capital of mining companies. This, in turn, has lead to major production cuts, layoffs, shut-downs of operating properties, and the deferral of new and expansion projects. These changes in the minerals industry have played a major role in the health of the economy. Operationally, the industry continues to develop new technologies that are making our work more efficient, more cost effective and more environmentally acceptable and safe. During downturns like this, companies generally pay closer attention to operational efficiencies and process optimization. Historically, new technologies and processes tend to be developed during down markets, and I believe we will see the same thing as companies strive to preserve liquidity and maintain or improve their margins. On the positive side, the drop in commodity prices has resulted in a reduction in operational costs, as the costs for fuel supplies and construction materials have decreased.

Jan 1, 2009

By F. Chavan

1. Introduction The new Cleuson-Dixence development project in the Valais region of the Swiss Alps, involves the construction of a new link between the Grande-Dixence dam (still world recordholder with a height of 300 m) and a power house on the banks of the Rhone consisting of approximately 20 km tunnels and shafts, and involving a fall of about 1900 m. This 1200 MW project will replace an existing 900 MW structure built in the 1960s, no longer considered efficient. The new project comprises a head race drift about 15.8 km long, a surge tank, an inclined cascade shaft 4,2 km long, and an underground power station. The work for lots C and D (head race drift from Tortin to Tracouet, surge tank, six adits ans the complete inclined shaft) was awarded to our group (Prader, Locher, SELL, Losinger, Evéquoz, Dénériaz, Imboden and Bouygues). The geological conditions are: Lower part of the shaft (300 m) : sedimentary - sandstone and soft tertiary sandstone. Middle and upper part (2600 m) : metamorphic - upper and lower carboniferous, interrupted by triasic chipping. The horizontal section (7 km) consists of mica

Jan 1, 1995

By S. S. Peng, Luo. Y.

In a shearer longwall mining operation, the longwall hits are responsible for breaking into and chipping the broken coal blocks away from the coal face. However, underground observations found that the bits being used were working under various degrees of wear. This wear can be reduced by using better-designed longwall bits and by properly selecting shearer operating parameters. A computer program was developed to simulate the performance of the longwall bits. The information required by the program are the shape of the bit head, the installation of the bits on the drum and the operation parameters. Through the simulations, the main factors affecting the bit-wearing process are identified. Suggestions are also made for improving the design of the longwall bits.

Jan 1, 1998

By Michel Gauthier

Several zinc showings, exhibiting many similarities to the well-known Balmat-Edwards zinc deposits of New York State, occur within the Grenville Supergroup strata of the Mont-Laurier Basin, Quebec. Metallogenic mapping programs have revealed much of the stratigraphic control of this mineralization. This control is observed on both regional and local scales. At the regional scale, these showings are confined to the perimeter of the Mt.-Laurier Basin, while at the local scale, a definite association between the zinc mineralization and dolomitic marble horizons is clearly exhibited from detailed mapping. These new exploration guidelines have proven to be useful for base-metal exploration in the Mt.-Laurier Basin and should be applicable to the entire Grenville Province.

Jan 1, 1983

By Harrison H. Roberts

A. We are aware that many who are in the audience have perhaps heard before some of the material which will be presented. Since our firm is more closely associated with the heavy construction industry our experience is more oriented in that direction. Notwithstanding this, the subject your program committee has asked us to present centers mainly in the earth-moving field. We find a common denominator between say, the stripping of a site to uncover an ore-body which will be developed by open-pit methods, and that of excavating & transporting materials for an embankment dam, airport or other project. Both are earth-moving problems and we offer for your consideration a means of determining the most favorable method, equipment selection and resultant cost. We do considerable studies involving rock excavation for tunnels, underground powerhouses, inclined and vertical shafts for penstocks, muck-removal, electrical cable & other related underground work. Hence, we believe we speak the same language.

Jan 1, 1972

By V 9. 0 / 300 dpi

Papua New Guinea (PNG) stretches from the equator to Latitude 12° South and from Indonesia's Irian Jaya Province in the west to the Solomon Islands in the east (Figure 1). The population totals 3.5 million people who are mostly concentrated in highland valleys on the main island and around the coast. This paper outlines the history of mining, describes the natural, cultural and regulatory setting of mineral discoveries and highlights, by example, some of the more idiosyncratic environ-mental aspects of mining developments in PNG. It concludes with remarks on the progress made in the fifteen years since environmental matters entered the agenda for the establishment of a new mine in PNG.

Jan 1, 1988

By E. Forssberg, T. Nordquist

Introduction In this technical note, pilot-scale tests with two types of gravity concentrators, the Knelson separator (Anon., 1983; Forssberg and Johansson, 1984) and the Mark VIIA Reichert spiral concentrator (Balderson, 1982; Forssberg and Johansson, 1984), are described. The experimental work was concentrated on the relatively untried Knelson separator. The materials tested have different concentration characteristics: one was an artificial ore with excellent liberation characteristics and with a wide difference in density between valuable and gangue minerals; the others include a spiral concentrate containing gold from the gravity circuit of Boliden, Sweden, an old scheelite tailing from Yxsjöberg, Sweden, and an auriferous ore, containing gold, that had not been crushed to full liberation. The latter three materials contained other heavy minerals, e.g. pyrite, that can interfere with concentration. Knelson separator The Knelson separator is a compact centrifugal separator with an active fluidized bed to capture heavy minerals. A centrifugal force equal to or exceeding 50 times the force of gravity acts on the particles. The strong centrifugal force traps the heavier particles in a series of rings located in the concentrator while gangue particles are flushed out (Fig. 1). The particular separator used in the tests has a 15-cm (6-in.) diam bowl and can process between ~70 and ~250 kg/h.

Jan 1, 1988

By E. Varouchakis

Spartan Spatial Random Fields (SSRF?s) provide a new geostatistical framework (Hristopulos, 2003) with applications targeting environmental risk assessment and natural resources estimation. SSRF?s have the ability to incorporate constraints based on physical laws in the statistical description and have proved to be computationally fast in the analysis of synthetic data sets. This paper presents an application of a specific SSRF model and a new local-error spatial estimator (Hristopulos, 2005) in the mapping of environmental pollutants using a real data set. A detailed comparison of the local SSRF estimator with a classical kriging method is presented. It is shown that the SSRF approach provides a competitive alternative for spatial estimation.

Jan 1, 2005

By Christopher E. Johansson, William J. Kohr, John W. Shield

Heap biooxidation is an economical means to treat refractory sulfidic ores. However, air flow limitations are a major obstacle in commercialization of this technology. Geobiotics, Inc. has developed a new process for heap biooxidation of sulfide ores that renders the ore more susceptible to bacterial oxidation. In this process, air and liquid flows in the heap are greatly improved by first removing clays and other fine particles from the ore. Gold bearing sulfides are recovered from the removed fines and separately biooxidized. Column biooxidations were conducted on two refractory sulfidic ores from which the fines had been removed in order to improve air flow through the column. Gold recoveries increased from 46% to 90% for a mill grade ore and from 52% to 80% for a low grade ore after biooxidation. Fines and clays in these ores had precluded whole ore heap biooxidation from occurring. This new process addresses the most significant problem of large scale heap biooxidation.

Jan 1, 1996

By Jonathan K. Hrica, CASSANDRA L. HOEBBEL, Jennica L. Bellanca

Accidents involving powered haulage and mobile equipment like haul trucks are a major safety concern in the U.S. mining industry. They account for more than 50 percent of surface mine fatalities each year [1]. A recent National Institute for Occupational Safety and Health (NIOSH) analysis of 91 fatal incidents identified loss of vehicle control and situational awareness as key contributors [2]. However, the first-hand perspectives of operators are often missing, emphasizing the need for deeper insights into operators’ decisionmaking, lessons learned, sensory cues and mental strategies used during near-miss events. The findings in this analysis will help inform the development of training and safety solutions to prevent or reduce haul truck accidents.

May 1, 2025

By Charles H. Grant

Communications in whatever we do, is one of the major problems we encounter. In an effort to provide a better understanding of the use of explosives, I am going to take a little different view of what explosives are, and how you might look at them as tools to fragment rock, and some of the problems encountered in doing so. First, let's take the explosive, and although there are many factors involved, I want you to consider these as being reduced to only two--shock strain imparted to the rock by the high early development of energy; and the other, the gas effect which is a combination of heat, moles of gas formed, rate of formation of these gases which develop pressures, etc..

Jan 1, 1968

By David A. Grisafe

Divided opinions concerning dredging-permit locations and boating uses on the Kansas River in northeastern Kansas led to a study of the recreation potential on the river by a legislatively mandated interagency group (five agencies) that included the Kansas Geological Survey (KGS). In addition, the KGS conducted its own study of the river corridor, encompassing the development, geology, and economic resources of the corridor (Brady and others, 1998). The corridor area is 12 mi wide and 140 mi long (171 river miles). Included in the study was the potential impact of restric¬tions to river dredging. The Kansas River and its floodplain in northeastern Kansas are underlain by Lower Permian and Upper Pennsylvanian limestones and shales. The river and its floodplain are the major sources of sand and gravel for northeastern Kansas, and the limestones along the river bluffs supply crushed stone and building stone. The population of the 10-county area bordering the river has grown by 20% since 1980, and now comprises nearly 40% of the state's population (U.S. Bureau of the Census, 1996). Projections (Floerchinger, 1992) indicate close to 50% of the Kansas population will reside in these counties by 2025, with a continued increase in the demand for aggregates. Factors such as floodplain width, price and availability of land, and overburden ratios tend to favor river dredging on the lower part of the river, and floodplain or pit dredging on the upper portion. The use of alternate sources of sand and gravel such as the Missouri and Arkansas Rivers would increase sand prices due to transportation costs to much of the 10-county area. In 1996, river and pit dredges along the Kansas River supplied more than 3 million tons of sand and gravel valued at about $8 million to northeastern Kansas. As a result of its study, the KGS had concerns with the idea of large recreation zones on the river that excluded river dredging in areas of presently large population and projected population growth. This controversial issue is likely to recur elsewhere.

Jan 1, 1999